… Genetic ancestry was used for subsequent comparisons between samples in terms of
genomic features in this study. Based on genetic ancestry, the age at diagnosis of mucosal …

… Median tumor purity (0.53 (IQR 0.38–0.67) was estimated on the obtained sequencing data
and was not significantly different between biopsy sites. Based on a previously described …

… Somatic landscape of familial BC The somatic mutational landscape differed between
tumours from BRCA1, BRCA2 and non-BRCA1/2 carriers (Figure 1; supplementary Figure S1, …

… However, retinoblastoma cases exist where mutations in RB1 have not been detected.
We used whole-genome sequencing to investigate the landscape of mutations in a cohort of …

… to generate enough DNA for reliable whole-genome sequencing (WGS). The disadvantages
… reveals intriguing differences between sites. The UV mutational signature is subtly different …

… [8], we performed whole-genome sequencing to characterize novel mutation-… difference
between small and large deletor subgroups with respect to gleason score suggests differences …

… might reveal novel mechanisms for gastric cancer (GC) tumorigenesis. Here, we analysis
structural variations (SVs) and mutational signatures via whole-genome sequencing of 168 …

… We present mutational signature analyses of 12,222 whole-genome–sequenced cancers
collected prospectively via the UK National Health Service (NHS) for the 100,000 Genomes …

… Here we use whole-genome sequencing to analyse … Signatures of multiple mutational
processes were revealed; some … of mutation, such that we could not detect differences between …

… We therefore leveraged the comprehensive resolution of whole-genome sequencing to
assess 51 tumor samples from 49 patients with CAR-19–treated large B-cell lymphoma. We …