… that WNT signaling would be down-regulated, due to the role of WNT signaling in stem cells
… Bone marrow cells from WT and Gata4 Prx-cKO mice were cultured in mouse MesenCult …

… Wnt signaling is an evolutionary cell-to-cell coordination mechanism and it is highly … stem
cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell …

… with a method for optogenetic control of Wnt signaling, we sought to determine whether
Wnt signaling is sufficient for inducing cell self-organization. We activated Wnt signaling in a …

… Using single cells RNA sequencing and high-dimensional flow cytometry, we demonstrate
… engagement of Wnt signaling. In humans, aging is associated with the coupled loss of Wnt/β-…

… 23], and a comparable system for mouse embryonic stem cells has been developed [24].
Three-… spatial dynamics of WNT signaling by defining a territory of active signaling as the region …

… Wnt signaling has been studied for its influence on cardiac and neural differentiation of …
pluripotent stem cells (iPSCs). The influence of Wnt signaling on the fate decision of stem cells is …

… that WNT signaling components are expressed in the human … , and observed evidence for
canonical WNT signaling only in the … or cell fate determination and differentiation in stem cells (…

… Together, these findings have questioned the nature of stem cell identity and function.
Here, … of stem cell fate and provided new insights into the mechanisms that regulate self-renewal. …

… In this Review, we discuss how YAP/TAZ control stem cell fate … /TAZ mediate stem cell
decisions between renewal and fate. … WNT signalling that cooperate to drive cardiomyocyte fate, …

… of the WNT signal remain ill-defined. Using a robust model of human NC formation based
on human pluripotent stem cells (hPSCs), we expose that the WNT signal modulates the axial …