GATA4 regulates mesenchymal stem cells via direct transcriptional regulation of the WNT signalosome
… that WNT signaling would be down-regulated, due to the role of WNT signaling in stem cells
… Bone marrow cells from WT and Gata4 Prx-cKO mice were cultured in mouse MesenCult …
… Bone marrow cells from WT and Gata4 Prx-cKO mice were cultured in mouse MesenCult …
Wnt signaling pathway: A comprehensive review
… Wnt signaling is an evolutionary cell-to-cell coordination mechanism and it is highly … stem
cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell …
cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell …
Optogenetic control of Wnt signaling for modeling early embryogenic patterning with human pluripotent stem cells
… with a method for optogenetic control of Wnt signaling, we sought to determine whether
Wnt signaling is sufficient for inducing cell self-organization. We activated Wnt signaling in a …
Wnt signaling is sufficient for inducing cell self-organization. We activated Wnt signaling in a …
Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway
H Kared, SW Tan, MC Lau, M Chevrier, C Tan… - Nature …, 2020 - nature.com
… Using single cells RNA sequencing and high-dimensional flow cytometry, we demonstrate
… engagement of Wnt signaling. In humans, aging is associated with the coupled loss of Wnt/β-…
… engagement of Wnt signaling. In humans, aging is associated with the coupled loss of Wnt/β-…
Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids
… 23], and a comparable system for mouse embryonic stem cells has been developed [24].
Three-… spatial dynamics of WNT signaling by defining a territory of active signaling as the region …
Three-… spatial dynamics of WNT signaling by defining a territory of active signaling as the region …
Wnt-Notch signaling interactions during neural and astroglial patterning of human stem cells
J Bejoy, B Bijonowski, M Marzano, R Jeske… - … Engineering Part A, 2020 - liebertpub.com
… Wnt signaling has been studied for its influence on cardiac and neural differentiation of …
pluripotent stem cells (iPSCs). The influence of Wnt signaling on the fate decision of stem cells is …
pluripotent stem cells (iPSCs). The influence of Wnt signaling on the fate decision of stem cells is …
Dynamics of WNT signaling components in the human ovary from development to adulthood
… that WNT signaling components are expressed in the human … , and observed evidence for
canonical WNT signaling only in the … or cell fate determination and differentiation in stem cells (…
canonical WNT signaling only in the … or cell fate determination and differentiation in stem cells (…
Tracing the dynamics of stem cell fate
L Chatzeli, BD Simons - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
… Together, these findings have questioned the nature of stem cell identity and function.
Here, … of stem cell fate and provided new insights into the mechanisms that regulate self-renewal. …
Here, … of stem cell fate and provided new insights into the mechanisms that regulate self-renewal. …
Control of stem cell renewal and fate by YAP and TAZ
JH Driskill, D Pan - Nature Reviews Molecular Cell Biology, 2023 - nature.com
… In this Review, we discuss how YAP/TAZ control stem cell fate … /TAZ mediate stem cell
decisions between renewal and fate. … WNT signalling that cooperate to drive cardiomyocyte fate, …
decisions between renewal and fate. … WNT signalling that cooperate to drive cardiomyocyte fate, …
WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest
GA Gomez, MS Prasad, M Wong, RM Charney… - …, 2019 - journals.biologists.com
… of the WNT signal remain ill-defined. Using a robust model of human NC formation based
on human pluripotent stem cells (hPSCs), we expose that the WNT signal modulates the axial …
on human pluripotent stem cells (hPSCs), we expose that the WNT signal modulates the axial …