… Taken together with our finding that the Wnt signal is received by HE 3 , these results
indicate that Fzd9b is required for HSPC development, downstream of fate specification, and …

… BMP4/SMAD signaling controls core transcriptional TFs through interaction with KLF4.
FGF4/ERK signaling promotes differentiation of mESCs through JNK/c-JUN and MEK/ERK …

… of CBC cells as intestinal stem cells. However, it was the advent of genetic lineage tracing
tools that brought final proof of CBC cell stemness: on the basis of a study of WNT signalling in …

… orchestrating spatial cell fate patterning. Here we present a microfluidic approach that
exposes human pluripotent stem cell (hPSC) colonies to spatiotemporally controlled morphogen …

… non-canonical Wnt signaling in hiPSC-derived S7 cells using syntetic … of human pluripotent
stem cells, and canonical Wnt signaling has been found to induce a posterior endoderm fate …

… of Wnt signaling in mediating cellular senescence in kidney parenchymal and stem cells, an
irreversible arrest of cell … We also highlight the therapeutic targets of Wnt signaling in kidney …

… In intestinal homeostasis, it is responsible for the maintenance of the stem cell pool via Wnt/β…
level of Wnt signaling (Dow et al., 2015). In this review we will discuss how Wnt signaling is …

… Below, we outline designs of Notch signal modulations between stem cells and their …
arrangements of cells underpin cell fate decisions during tissue morphogenesis (Figure 1). …

… This study identified the IGF as a critical signal maintaining the diversity of mesoderm cell
fates, elucidated its molecular mechanism, and developed IGF and CK2 inhibition as …

… These conditions are dynamically controlled based on the balance between cell cycle
activators and inhibitors. Canonical WNT signaling induces proliferation of cancer stem cells (…