… products, such as lipopolysaccharide (LPS), lipoproteins, and … A second high-affinity,
zinc-dependent binding site on the … NFκB regulates the transcription of genes for many cytokines, …

… Regarding zinc, no further induction of cytokine production … is most likely regulated via
different pathways by zinc and vitamin … TSST-1 is a superantigen which activates T cells via the T …

… by endogenous and exogenous stimuli including cytokines, … that MT3 negatively regulates
the highly inflammatory caspase-… We further queried the impact of MT3 on LPS-induced sepsis…

… Further, zinc induces the cysteine-rich zinc-binding protein metallothionein, which serves …
IL-6 functions as an enhancer of the zinc importer zinc transporter protein (Zrt)-, iron-regulated …

… caused by the superantigens, staphylococcal enterotoxins A … FcɛRI) induces MT1 and
MT2 in mouse basophils to regulate … M1 polarization by IFNγ and LPS but does not affect M2 …

… a key role in regulating intracellular zinc distribution after T … expressed under high zinc
concentrations and induces IFN-γ … TSST is a bacterial superantigen that binds directly to the Vβ …

… further up-regulating many other proinflammatory cytokines (10–… To study the significance
of tightly regulated blood pH ex vivo, … all our findings with lipopolysaccharide-free HMGB1 and …

… and systemic effects of exotoxins such as superantigens trigger multi-tier dynamic reactions
… with bacterial LPS and IL-1β. Interestingly the recombinant protein does not induce the …

… addition, cytokine production is markedly influenced by zinc … hypothesized that
activation-induced zinc influx is mediated … finding using a T cell-DC-superantigen system (16). In …

… Importantly, zinc-binding superantigens remain on the cell … Furthermore, TCR function is
regulated by intracellular zinc … Since OSM expression is induced by lipopolysaccharide (LPS), it …