… mainly via the degradation of adenosine 5′-triphosphate (… Adenosine and ATP acting at
different classes of receptors … 1 receptor (P2Y 1 R) subtype [1,2], whereas adenosine induces …

… On the basis of adenosine’s binding affinity, these A2 receptors are subdivided into … as A2A
receptors having the higher affinity and A2B receptors having the lower affinity for adenosine […

… show that the enigmatic adenosine A2B receptor (A2B) is … A2B exhibited sarcopenia,
diminished muscle strength, and reduced energy expenditure (EE), whereas pharmacological A2B …

… A 2A and A 2B adenosine receptors (ARs) are closely related G protein-coupled receptor …
Despite their almost identical binding sites for adenosine, A 2A ARs are activated by low (…

… A2A Adenosine Receptors (A2A ARs) The activation of A2A receptor elicits the stimulation
of adenylate cyclase which in turn elevates the intracellular cAMP [12]. A2A ARs are highly …

… family of G protein-coupled receptors (GPCRs). Until recently… for the endogenous agonist
adenosine and therefore presumed … adenosine concentration, the sensitisation of the receptor …

… The A2A-adenosine receptors do not appear to be up-regulated,2425 although there is …
A2A-adenosine receptors in striatum after chronic ingestion of caffeine by mice.The A2B-receptor…

… It is known that the two adenosine receptors are expressed in different areas of the central
nervous system. Owing to the implication of the adenosine receptor in neuromodulation, we …

Adenosine is a signaling molecule, which, by activating its receptors, acts as an important
player after cerebral ischemia. Here, we review data in the literature describing A 2B R-…

… Accumulating evidence suggests that inhibiting adenosine-generating ecto-enzymes (CD39
and CD73) and/or adenosine A2A or A2B receptors (R) stimulates antitumor immunity and …