[HTML][HTML] Selective androgen receptor modulators: the future of androgen therapy?

AR Christiansen, LI Lipshultz, JM Hotaling… - Translational …, 2020 - ncbi.nlm.nih.gov
… Selective androgen receptor modulators (SARMs) are small molecule drugs that function
as either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …

Selective androgen receptor modulators: current knowledge and clinical applications

ZJ Solomon, JR Mirabal, DJ Mazur… - Sexual medicine …, 2019 - academic.oup.com
… Selective androgen receptor modulators (SARMs) differentially bind to androgen receptors
depending on each SARM’s chemical structure. As a result, SARMs result in anabolic cellular …

Androgen receptor modulators: a review of recent patents and reports (2012-2018)

S Fujii, H Kagechika - Expert opinion on therapeutic patents, 2019 - Taylor & Francis
… The actions of androgen can be classified into androgenic effects, which refer to the actions
… of selective androgen receptor modulators (SARMs), which separate the androgenic effects …

[HTML][HTML] Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth

MD Nyquist, LS Ang, A Corella… - The Journal of …, 2021 - Am Soc Clin Investig
… Selective androgen receptor modulators (SARMs) were developed as a substitute for steroidal
androgens to treat a range of conditions including partial androgen insensitivity syndrome …

… for deleterious effect in recreational and athletic use of selective androgen receptor modulators (SARMs) in lieu of anabolic androgenic steroids: A narrative review

SB Machek, TD Cardaci, DT Wilburn, DS Willoughby - Steroids, 2020 - Elsevier
androgen receptor (AR) binding-mediated actions. More recently, selective AR modulators
(… Note: The above list is not an exhaustive list of all selective androgen receptor modulators (…

[HTML][HTML] Systematic review of safety of selective androgen receptor modulators in healthy adults: implications for recreational users

JD Vignali, KC Pak, HR Beverley, JP DeLuca… - Journal of …, 2023 - mdpi.com
Selective Androgen Receptor Modulators (SARMs) are not FDA approved, and obtaining
SARMs for personal use is illegal. Nevertheless, SARM use is increasingly popular amongst …

Selective androgen receptor modulators (SARMs) as pharmacological treatment for muscle wasting in ongoing clinical trials

GWPD Fonseca, E Dworatzek, N Ebner… - Expert opinion on …, 2020 - Taylor & Francis
… with testosterone, selective androgen receptor modulators (SARMs) have been developed
[Citation14]. SARMs have shown a targeted therapeutic effect on the androgen receptor (AR), …

Analysis of supplements available to UK consumers purporting to contain selective androgen receptor modulators

AE Leaney, P Beck, S Biddle, P Brown… - Drug testing and …, 2021 - Wiley Online Library
… Selective androgen receptor modulators (SARMs) are compounds with specific androgenic
… The reported androgenic properties have resulted in their use by athletes, and consequently …

Evaluation of ostarine as a selective androgen receptor modulator in a rat model of postmenopausal osteoporosis

DB Hoffmann, M Komrakova, S Pflug… - Journal of bone and …, 2019 - Springer
Selective androgen receptor modulators (SARMs) have shown beneficial effects on muscle
wasting, general physical function and bone properties in male mammals. However, data on …

[HTML][HTML] Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus

I Simitsidellis, A Esnal-Zuffiaure… - Journal of …, 2019 - joe.bioscientifica.com
androgen receptor modulators (SARMs) have been proposed as therapeutics for women
suffering from breast cancer, muscle wasting or urinary incontinence. The androgen receptor (…