Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus

I Simitsidellis, A Esnal-Zuffiaure… - Journal of …, 2019 - joe.bioscientifica.com
androgen receptor modulators (SARMs) have been proposed as therapeutics for women
suffering from breast cancer, muscle wasting or urinary incontinence. The androgen receptor (…

Drug-induced liver injury from enobosarm (ostarine), a selective androgen receptor modulator

H Bedi, C Hammond, D Sanders, HM Yang… - ACG case reports …, 2021 - journals.lww.com
… Selective androgen receptor modulators (SARMs) have been developed to enhance muscle
bulk without the side effects associated with exogenous androgen steroids. We report a …

Drug‐induced liver injury by selective androgenic receptor modulators

JE Flores, S Chitturi, S Walker - Hepatology communications, 2020 - journals.lww.com
… Selective androgenic receptor modulators (SARMs) have not been approved by the US
Food and Drug Administration but they are heavily promoted as alternatives to androgenic …

[HTML][HTML] Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review

T Koller, P Vrbova, I Meciarova, P Molcan… - World journal of …, 2021 - ncbi.nlm.nih.gov
… Core Tip: Ligandrol and ostarine are selective androgen receptor modulators with a
presumably more favorable side effect profile. They are often misused by amateur body builders …

The forensic response after an adverse analytical finding (doping) involving a selective androgen receptor modulator (SARM) in human athlete

P Kintz - Journal of pharmaceutical and biomedical analysis, 2022 - Elsevier
… Selective androgen receptor modulators (SARMs) are a class of drugs presenting identical
anabolic properties to anabolic steroids in addition to marked reduced androgenic effects. …

Androgen receptor modulation optimized for response—splice variant: a phase 3, randomized trial of galeterone versus enzalutamide in androgen receptor splice …

ME Taplin, ES Antonarakis, KJ Ferrante, K Horgan… - European urology, 2019 - Elsevier
… The androgen receptor (AR) is central to tumor growth, and androgen deprivation therapy
(ADT) is the primary therapy [2]. The AR pathway remains a driver of tumor growth in most …

Simultaneous detection of different chemical classes of selective androgen receptor modulators in urine by liquid chromatography-mass spectrometry-based …

C Stacchini, F Botrè, F Comunità, X de la Torre… - … of pharmaceutical and …, 2021 - Elsevier
Analytical procedures to detect the misuse of selective androgen receptor modulators in
human urine, targeting either the parent drugs and/or their main metabolites, were developed …

Androgens and androgen receptor actions on bone health and disease: from androgen deficiency to androgen therapy

JF Chen, PW Lin, YR Tsai, YC Yang, HY Kang - Cells, 2019 - mdpi.com
androgen receptor modulators may provide new approaches for the treatment of osteoporosis
and fractures as well as building stronger bones in diseases dependent on androgens/AR …

[HTML][HTML] Selective androgen receptor modulator, S42 has anabolic and anti-catabolic effects on cultured myotubes

Y Muta, T Tanaka, Y Hamaguchi, N Hamanoue… - … and biophysics reports, 2019 - Elsevier
… We previously identified a novel selective androgen receptor modulator, S42, that does not
stimulate prostate growth but has a beneficial effect on lipid metabolism. S42 also increased …

Investigation of the metabolism of the selective androgen receptor modulator LGD‐4033 in equine urine, plasma and hair following oral administration

C Cutler, M Viljanto, P Hincks… - Drug testing and …, 2020 - Wiley Online Library
… of selective androgen receptor modulators (SARMs) that are being developed by the
pharmaceutical industry to provide the therapeutic benefits of anabolic androgenic steroids, without …