Strategies towards the synthesis of anti-tuberculosis drugs

HB Rode, DM Lade, R Grée, PS Mainkar… - Organic & …, 2019 - pubs.rsc.org
… of drug resistance. Hence, the development of new analogs and new drugs which can treat
drug… In this report, we reviewed the strategies towards the synthesis of antituberculosis drugs. …

Safety implications of combined antiretroviral and anti-tuberculosis drugs

M Cerrone, M Bracchi, S Wasserman… - … opinion on drug …, 2020 - Taylor & Francis
… anti-TB drugs used for sensitive-, drug-resistant (DR) and latent TB are discussed. Overlapping
drug … Expert opinion: New antiretroviral and anti-tuberculosis drugs have been recently …

Modern anti-tuberculosis drugs and their classification. Part I: first-line drugs

LA Kayukova, EA Berikova - Pharmaceutical Chemistry Journal, 2020 - Springer
… of drug-sensitive (DS) tuberculosis (TB) with first-line drugs is … extensively drug-resistant
(XDR) TB with second-line drugs, … Anti-tuberculosis drugs are traditionally classified depending …

Gut microbiota associated with pulmonary tuberculosis and dysbiosis caused by anti-tuberculosis drugs

Y Hu, Q Yang, B Liu, J Dong, L Sun, Y Zhu, H Su… - Journal of Infection, 2019 - Elsevier
… Another important part of the present study was to observe the effects of the anti-TB drugs
drugs used in anti-TB treatment have been rarely described.10, 17 Effective treatment of drug-…

[HTML][HTML] Handling the hurdles on the way to anti-tuberculosis drug development

PF Dalberto, EV De Souza, BL Abbadi… - Frontiers in …, 2020 - frontiersin.org
… The pathway to find a new TB drug, however, is arduous and … interested in anti-TB drug
development, which goes from … found along the TB drug development process and illustrates …

Targeting MmpL3 for anti-tuberculosis drug development

JR Bolla - Biochemical Society Transactions, 2020 - portlandpress.com
… to address bottlenecks in drug development, drug repurposing of approved drugs is being
Drug-repurposing strategies can be used to identify new anti-TB drug candidates that have …

[HTML][HTML] Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs

JES Nunes, MA Duque, TF de Freitas, L Galina… - Molecules, 2020 - mdpi.com
… measures and the increase of drug-resistant M. tuberculosis … targets for the development
of new drugs to treat TB. This … be potentially explored towards selective drug development. …

Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol

L Zhang, Y Zhao, Y Gao, L Wu, R Gao, Q Zhang… - Science, 2020 - science.org
… are recognized as targets for the anti-tuberculosis drug ethambutol. In this study… Most
drug-resistant mutations are located near the … and the development of new anti-tuberculosis

[HTML][HTML] Anti-tuberculosis treatment strategies and drug development: challenges and priorities

VA Dartois, EJ Rubin - Nature Reviews Microbiology, 2022 - nature.com
… proposed to accelerate the development of curative drug regimens. Not included here are a
… clinical drug candidates and their targets, nor a list of clinical trials of single drugs and drug

[HTML][HTML] Multicomponent crystals of anti-tuberculosis drugs: a mini-review

E Batisai - RSC advances, 2020 - pubs.rsc.org
drugs reveals that, despite many drug candidates showing initial promise, the emergence
of drug … It quickly became evident that single-drug therapy would most likely result in the …