… escape experiments with the original virus and the L50F variant. We found that preexisting
… Representative images from concentration-response antiviral treatment assays are shown …

… nirmatrelvir is essential to enhance antiviral potency, limit toxicity… antiviral treatment, especially
the rapid reduction of viral load, is expected to improve patient outcome but also limit virus …

… PGT121 resistance had no change in viral load compared to baseline following … viral
variants had brief dips in viral load (Fig. 3a and Supplementary Table 10). Notably, baseline virus …

… antiretroviral treatment enabling clinical trial (LATTE-1), oral CAB plus two NRTIs suppressed
viral … The mutations in the drug-resistant viral variants found in populations of treated …

… anti-retroviral therapy (ART) has revolutionized the treatment … -HIV-1 antibodies clear the
virus, directly kill infected cells and … no emergence of double-resistant viral variants. Thus, the …

… virus. Some endemic lineages, for example 1l and 4r, are known to respond less well to
direct-acting antiviral treatment … with the highly prevalent genotype 4k variant found in Gabon, the …

… circulating viral variants in resolver patients or causing a replacement with escape variants
… T/G, were considered relevant in antiviral treatment outcomes [124]. Both rs12979860 and …

… Calibrating controls (including those with low viral loads and low abundance variants in
known proportion) are frequently missing in published reports (Table 2). Use of capture probes …

… Virus-1 (HIV-1) due to antiretroviral treatment pressure, leading to viral rebound and treatment
… Furthermore, drug-resistant HIV variants can be transmitted to treatment-naive individuals …

… within the cell or emergence of viral variants with less susceptibility to 3TC inhibition [13]. …
Presumably, antiretroviral treatment delayed virus appearance but successive virus spread …