H3K36me2/3 binding and DNA binding of the DNA methyltransferase DNMT3A PWWP domain both contribute to its chromatin interaction
M Dukatz, K Holzer, M Choudalakis, M Emperle… - Journal of molecular …, 2019 - Elsevier
… DNA suggests a combined binding to H3K36me2/3 and DNA. We show here that the DNMT3A
PWWP domain binds to DNA … and specificity of methylated H3K36 and DNA binding of the …
PWWP domain binds to DNA … and specificity of methylated H3K36 and DNA binding of the …
Domain structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA methyltransferases
… Rett syndrome is known to be caused mainly by a mutation in the MeCP2 gene, of which
the translation product specifically binds to methylated DNA and is a component of the …
the translation product specifically binds to methylated DNA and is a component of the …
Methods for analysis of specific DNA methylation status
MJ Pajares, C Palanca-Ballester, R Urtasun… - Methods, 2021 - Elsevier
… In the last group, proteins with methylation binding domains or antibodies against methyl
cytosines are used to recognize methylated DNA. In this review, we provide the theoretical …
cytosines are used to recognize methylated DNA. In this review, we provide the theoretical …
MBD5 and MBD6 couple DNA methylation to gene silencing through the J-domain protein SILENZIO
… Here, we describe two Arabidopsis thaliana methyl-CpG–binding domain proteins, MBD5
and MBD6, that are recruited to chromatin by recognition of CG methylation, and redundantly …
and MBD6, that are recruited to chromatin by recognition of CG methylation, and redundantly …
[HTML][HTML] Toward a mechanistic understanding of DNA methylation readout by transcription factors
… available to measure the impact of methylated DNA on TF binding. By relating position-…
ZFPs, proteins with a canonical methyl-binding domain, and specialized TFs such as p53 […
ZFPs, proteins with a canonical methyl-binding domain, and specialized TFs such as p53 […
A group of SUVH methyl‐DNA binding proteins regulate expression of the DNA demethylase ROS1 in Arabidopsis
X Xiao, J Zhang, T Li, X Fu, V Satheesh… - Journal of integrative …, 2019 - Wiley Online Library
… domain known to bind methylated DNA, we tested whether the SUVH proteins could bind …
SUVH3 could only bind to methylated MEMS (Figure 3C) and the binding was competitively …
SUVH3 could only bind to methylated MEMS (Figure 3C) and the binding was competitively …
Molecular mechanism of methyl-dependent and spatial-specific DNA recognition of c-Jun homodimer
LH Bie, JW Fei, J Gao - Journal of Molecular Modeling, 2021 - Springer
… proteins have structurally distinct DNA-binding domains, they share a common methyl-Arg-…
SRA domain recognizes methylated DNA by flipping 5mC from a hemi-methylated CpG out …
SRA domain recognizes methylated DNA by flipping 5mC from a hemi-methylated CpG out …
Sensitivity of transcription factors to DNA methylation
… a DNA-binding domain, a trans-activating domain, which binds other … domain, which regulates
their activity (Figure 1A). TFs … to binding methylated DNA using structural information and a …
their activity (Figure 1A). TFs … to binding methylated DNA using structural information and a …
Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A.Z deposition
… Although MBD9 contains a methyl-CpG-binding domain, it is predicted not to bind methylated
DNA since it lacks key conserved residues required for mCpG binding 61 . Consistently, …
DNA since it lacks key conserved residues required for mCpG binding 61 . Consistently, …
Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation
S Kaluscha, S Domcke, C Wirbelauer, MB Stadler… - Nature …, 2022 - nature.com
… an MBD-like domain, also known as a TAM (TIP5/ARBP/MBD) domain, were … bind methylated
DNA 10,11 . Only four MBD proteins harbor a functional domain that binds methylated DNA …
DNA 10,11 . Only four MBD proteins harbor a functional domain that binds methylated DNA …
相关搜索
- dna recognition methyl cpg binding domain
- methylated dna binding domain proteins
- methylated dna selective anchoring
- methylated dna effect of cpg methylation
- methylated dna core region
- methyl cpg active dna demethylation
- dna binding affinity
- dna binding proteins molecular dynamics simulations
- domain deletion second dna binding site
- mammalian dna methyltransferase pwwp domain
- methylated dna dynamics simulations
- substrate inhibition second dna binding site
- domain deletion human dna methyltransferase
- methyl cpg recognition of methylated dna
- cpg methylation dna binding protein
- methyl cpg dna hyper methylation