… on the pathological mechanism of osteoporosis, the research on … of epigenetic mechanisms
in the regulation of bone metabolism, we mainly review the research progress on epigenetic …

… Since the osteoclast is the only cell able to induce bone resorption, investigations of bone
disease pathology have focused primarily on the mechanisms of osteoclast differentiation, …

… in the epigenetic regulation of bone remodeling. Specifically, miRNAs regulate bone …
Additional genetic pathologies affecting bone tissue comprise sclerosteosis (SOST) types 1 …

… activity of different cell types in bone tissue. The discovery of miRNA … bone. Various studies
have shown that miRNA deregulation mediates the progression of bone-related pathologies, …

… Epigenetic marks in MSCs can be amplified … epigenetic regulation of MSC homeostasis,
emphasizing its contributions to organismal health and disease. Understanding these epigenetic …

… the bone remodeling process described in human studies that address the epigenetic regulation
… contributor to pathological conditions, efforts to investigate the epigenetic marks in OP …

… bone resorption. The lineage-specific differentiation of bone cells requires an epigenetic
regulation … better understanding of the epigenetic mechanisms of both normal and pathological …

… epigenetic control, which we review here. We focus on epigenetic regulatory proteins that
control the … This review focused on epigenetic mechanisms and enzymes that control skeletal …

… Non-coding RNAs are another layer of epigenetic regulation closely linked to mRNA-related
and post-trascriptional events in bone cancer progression [18]. Single miRNAs having …

… the fate of MSCs, regulating epigenetic status and influencing gene expression related to
bone microenvironment remodeling. This suggests that epigenetic regulation appears to be an …