Outcome of pregnancies in female patients with inflammatory bowel diseases treated with vedolizumab

A Moens, K van Hoeve, E Humblet… - Journal of Crohn's …, 2019 - academic.oup.com
… antibody approved for the treatment of inflammatory bowel diseases [IBD], but without …
vedolizumab might affect this process. We aimed to evaluate pregnancy outcomes in vedolizumab

Real-world effectiveness of vedolizumab in inflammatory bowel disease: week 52 results from the Swedish prospective multicentre SVEAH study

C Eriksson, S Rundquist… - Therapeutic …, 2021 - journals.sagepub.com
vedolizumab are scarce. We aimed to assess the long-term clinical effectiveness of vedolizumab
in inflammatory bowel disease (… vedolizumab or any of its excipients), prior exposure to …

[HTML][HTML] Efficacy and safety of vedolizumab subcutaneous formulation in a randomized trial of patients with ulcerative colitis

WJ Sandborn, F Baert, S Danese, Ž Krznarić… - Gastroenterology, 2020 - Elsevier
vedolizumab SC for maintenance who achieved clinical remission at week 52 increased with
increasing vedolizumab exposure … treatments in inflammatory bowel disease, which ranged …

Vedolizumab tissue concentration correlates to mucosal inflammation and objective treatment response in inflammatory bowel disease

RWM Pauwels, E Proietti… - … Bowel Diseases, 2021 - academic.oup.com
… The association between vedolizumab (VDZ) exposure and treatment response is unclear
and seems insufficiently explained by serum levels. The aim of this study was to assess the …

Real‐world data on switching from intravenous to subcutaneous vedolizumab treatment in patients with inflammatory bowel disease

V Bergqvist, J Holmgren, D Klintman… - Alimentary …, 2022 - Wiley Online Library
… time on IV vedolizumab are … IV vedolizumab before the switch was 26.1 months (IQR
9.5–52.9). The wide IQR illustrates heterogeneity in terms of previous exposure time to vedolizumab

Comparative outcomes and safety of vedolizumab vs tumor necrosis factor antagonists for older adults with inflammatory bowel diseases

S Singh, AT Iversen, KH Allin, T Jess - JAMA Network Open, 2022 - jamanetwork.com
exposure of interest was treatment with vedolizumab, and the primary comparator was treatment
with TNF antagonists. We considered patients as being continuously exposedexposure

Vedolizumab is effective and safe in real-life treatment of inflammatory bowel diseases outpatients: a multicenter, observational study in primary inflammatory bowel …

A Tursi, G Mocci, R Faggiani, L Allegretta… - European journal of …, 2019 - Elsevier
… in managing ulcerative colitis (UC) and Crohn's disease (CD) patients with vedolizumab (VDZ)
are … in inflammatory bowel diseases (IBD) outpatients in primary gastroenterology centers. …

Effect of vedolizumab dose intensification on serum drug concentrations and regain of response in inflammatory bowel disease patients with secondary loss of …

A Outtier, L Wauters, JF Rahier, P Bossuyt… - …, 2021 - Wiley Online Library
… While we show an association between higher drug exposure after dose escalation and
regain of response, baseline VDZ serum concentrations cannot predict successful outcome of …

Mucosal eosinophilia is an independent predictor of vedolizumab efficacy in inflammatory bowel diseases

EM Kim, C Randall, R Betancourt… - … Bowel Diseases, 2020 - academic.oup.com
… Our findings of an inferior response to vedolizumab after the previous failure or exposure of
anti-TNF therapies are confirmed by similar reports in both CD and UC patients. The studies …

… of developing Crohn's disease or ulcerative colitis in 17 018 patients while under treatment with anti‐TNFα agents, particularly etanercept, for autoimmune diseases …

J Korzenik, MD Larsen, J Nielsen… - Alimentary …, 2019 - Wiley Online Library
disease. No patients in the study population were allowed to have a diagnosis of ulcerative
colitis (UC) or Crohn's disease … with autoimmune diseases who had been exposed to anti-…