A clinical decision support tool may help to optimise vedolizumab therapy in Crohn's disease

PS Dulai, A Amiot, L Peyrin‐Biroulet… - Alimentary …, 2020 - Wiley Online Library
… in CD than in ulcerative colitis (UC). Notwithstanding that prior exposure to a TNF antagonist
… help overcome the current gap in personalised medicine for inflammatory bowel disease. …

Crohn's disease and environmental contamination: Current challenges and perspectives in exposure evaluation

QM Tenailleau, C Lanier, C Gower-Rousseau… - Environmental …, 2020 - Elsevier
… Along with ulcerative colitis, Crohn’s disease (CD) is one of the two inflammatory bowel
diseases (IBDs). It is a chronic disease in which severe inflammation of the digestive tract results …

Monitoring vedolizumab and ustekinumab drug levels in patients with inflammatory bowel disease: hype or hope?

D Alsoud, S Vermeire, B Verstockt - Current opinion in pharmacology, 2020 - Elsevier
… Interestingly, only those patients who were persistently positive for AVAs experienced a
meaningful decrease in vedolizumab exposure and did not achieve clinical remission at the end …

Comparison of short‐and long‐term effectiveness between ustekinumab and vedolizumab in patients with Crohn's disease refractory to anti‐tumour necrosis factor …

L Manlay, G Boschetti, B Pereira… - Alimentary …, 2021 - Wiley Online Library
… All Crohn's disease patients treated with ustekinumab or vedolizumab after exposure to
at least one anti-TNF agent were included from two referral centres. Primary endpoint was …

Vedolizumab in the treatment of ulcerative colitis: an evidence-based review of safety, efficacy, and place of therapy

N Takatsu, T Hisabe, D Higashi, T Ueki, T Matsui - Core evidence, 2020 - Taylor & Francis
… (UC), the two major types of inflammatory bowel disease (IBD), are chronic remitting/…
exposure. No increased risk of any infection or serious infection was associated with VDZ exposure. …

[HTML][HTML] Postoperative outcomes after preoperative ustekinumab exposure in patients with Crohn's disease: a systematic review and meta-analysis

R Garg, BP Mohan, S Ponnada… - Annals of …, 2021 - ncbi.nlm.nih.gov
… UST has shown good efficacy and safety similar to anti-TNF agents and vedolizumab in the
… impact of vedolizumab on postoperative outcomes suggested vedolizumab exposure was …

Ustekinumab and vedolizumab are equally safe and effective in elderly Crohn's disease patients

GG Gebeyehu, J Fiske, E Liu, JK Limdi… - Digestive Diseases and …, 2023 - Springer
vedolizumab infusion. For patients receiving ustekinumab, Harvey-Bradshaw Index was
monitored by inflammatory bowel disease … anti-TNF-exposed patients showed no difference in …

Risk of postoperative complications among ulcerative colitis patients treated preoperatively with vedolizumab: a matched case-control study

JY Kim, K Zaghiyan, A Lightner, P Fleshner - BMC surgery, 2020 - Springer
… revolutionized the medical management of inflammatory bowel disease (IBD). Despite these
… case matching vedolizumab exposed, anti-TNF exposed and no biologic exposed patients. …

Association between vedolizumab and postoperative complications in IBD: a systematic review and meta-analysis

D Guo, K Jiang, J Hong, M Zhang, Y Shi… - … of Colorectal Disease, 2021 - Springer
vedolizumab (VDZ) therapy on postoperative complications in inflammatory bowel disease
(IBD) … During the operation, the time of intestinal exposure should also be reduced to keep the …

Incidence of arthritis/arthralgia in inflammatory bowel disease with long-term vedolizumab treatment: post hoc analyses of the GEMINI trials

BG Feagan, WJ Sandborn, JF Colombel… - Journal of Crohn's …, 2019 - academic.oup.com
… In post-marketing safety studies, joint-related events, including mostly arthralgia, were
infrequent non-serious events [526 events during 46798 patient-years of vedolizumab exposure; …