Phenolic compounds that cross the blood–brain barrier exert positive health effects as central nervous system antioxidants
D Velásquez-Jiménez, DA Corella-Salazar… - Food & Function, 2021 - pubs.rsc.org
… These are all components of the gut–liver–brain axis, … health effects along the way, in fact,
a phenolic may not strictly require access to the brain, since it can induce indirect health effects …
a phenolic may not strictly require access to the brain, since it can induce indirect health effects …
[HTML][HTML] The blood–brain barrier in health and disease: Important unanswered questions
CP Profaci, RN Munji, RS Pulido… - Journal of Experimental …, 2020 - rupress.org
… This “blood–brain barrier” is initiated during angiogenesis via … Blood–brain barrier dysfunction
contributes to pathology in a … regarding the blood–brain barrier in health and disease. …
contributes to pathology in a … regarding the blood–brain barrier in health and disease. …
Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health
A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
… of probiotic-promoted neuroprotective effects in AD studies remain to be determined but
may reflect positive effects on gut barrier health leading to improved immune and metabolic …
may reflect positive effects on gut barrier health leading to improved immune and metabolic …
Blood-brain barrier permeability and physical exercise
MA Małkiewicz, A Szarmach, A Sabisz… - Journal of …, 2019 - Springer
… numerous beneficial health effects. Epidemiological studies indicate that physical activity
leads to systemic adaptations and an elongated health-span, thus time of life in good health, in …
leads to systemic adaptations and an elongated health-span, thus time of life in good health, in …
Healthy aging and the blood–brain barrier
… BM with normal aging affect all components and are specific to each brain region. These
changes are likely to have effects on local microvascular function that impact the normal …
changes are likely to have effects on local microvascular function that impact the normal …
[HTML][HTML] Blood–brain barrier dynamics to maintain brain homeostasis
M Segarra, MR Aburto, A Acker-Palmer - Trends in neurosciences, 2021 - cell.com
… The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …
The blood-brain barrier in aging and neurodegeneration
… This barrier, however, breaks down with age and further disruption … barrier, and discuss
current drugs and therapeutics that maintain barrier integrity and the recent discoveries of effects …
current drugs and therapeutics that maintain barrier integrity and the recent discoveries of effects …
Regulation of blood–brain barrier integrity by microglia in health and disease: a therapeutic opportunity
PT Ronaldson, TP Davis - Journal of Cerebral Blood Flow & …, 2020 - journals.sagepub.com
… Such activation correlates with dysfunction of the blood–brain barrier (BBB), which is an
early event in stroke 3 and Alzheimer’s disease. In this review, we will discuss direct effects of …
early event in stroke 3 and Alzheimer’s disease. In this review, we will discuss direct effects of …
Increase in blood–brain barrier leakage in healthy, older adults
ICM Verheggen, JJA de Jong, MPJ van Boxtel… - Geroscience, 2020 - Springer
Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which
affects neuronal functioning. Currently, dynamic contrast-enhanced (DCE) MRI is the …
affects neuronal functioning. Currently, dynamic contrast-enhanced (DCE) MRI is the …
Peripheral inflammation and blood–brain barrier disruption: effects and mechanisms
X Huang, B Hussain, J Chang - CNS neuroscience & …, 2021 - Wiley Online Library
… The blood–brain barrier (BBB) is an important physiological barrier that separates the
central nervous system (CNS) from the peripheral circulation, which contains inflammatory …
central nervous system (CNS) from the peripheral circulation, which contains inflammatory …
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