… Adenosine receptor dysfunction is also involved in the pathology … , the adenosine receptor
balance theory is important for brain … Researchers also found that the c-fos immune response …

… of adenosine receptors, could have a role in the onset or the development of central nervous
system … ADA1 plays a crucial role in adaptive immune system development and exhibits an …

… through the interaction with four adenosine receptors (ARs), … the effect of adenosine on the
immune system is deleterious, … and damage, extracellular brain adenosine concentration is …

… Thus it is important to examine how adenosine receptor expression is regulated in the
brain under normal conditions and whether or not this regulation might be disturbed in mood …

… On the other hand, adenosine, an endogenous purine-based nucleoside that is expressed
… its G-protein-coupled receptors (A1, A2A, A2B and A3). Adenosine receptors (ARs) are thus …

… Notably, disruption of adenosine homeostasis in the brain under various pathophysiological
… two decades, adenosine receptors (particularly A 1 and A 2A adenosine receptors) have …

… against secondary brain injury. Evidence from stroke and inflammatory disease models
suggests that adenosine signaling through the G protein-coupled A 3 adenosine receptor (A 3 AR…

… each adenosine receptor as the basis of ligand production and describes clinical studies of
adenosine receptor… does not readily penetrate the blood–brain barrier [50]. There are several …

… system (CNS), is associated with chronic activation of an innate immune response. In addition,
in … sclerosis there is an infiltration of immune cells across the blood brain barrier (BBB) [7]. …

… of adenosine, it has been increasingly recognized as a key mediator of the immune response.
… elucidate the regulatory roles of adenosine receptors in the development and progression …