[HTML][HTML] A phase IIb, randomised, parallel-group study: the efficacy, safety and tolerability of once-daily umeclidinium in patients with asthma receiving inhaled …

E Kerwin, S Pascoe, Z Bailes, R Nathan… - Respiratory …, 2020 - Springer
… UMEC is a highly effective bronchodilator that leads to improved lung function when
administered as a single bronchodilator on top of FF in subjects with fully reversible, uncontrolled/…

[HTML][HTML] Comparison of effectiveness using different dual bronchodilator agents in chronic obstructive pulmonary disease treatment

SL Cheng - Journal of Clinical Medicine, 2021 - mdpi.com
therapy, dual bronchodilator agents with a combination of LABA and LAMA was an important
therapy … exacerbations (Group D) should be treated with dual bronchodilator agents initially…

Dual–Versus Mono–Bronchodilator Therapy in Moderate to Severe COPD: A Meta-analysis

M Lipari, PB Kale-Pradhan… - Annals of …, 2020 - journals.sagepub.com
… that dual bronchodilator therapy compared with LABA might result in better symptom control,
with the FEV 1 reaching the MCID with the LAMA component of combination therapy driving …

Beyond dual bronchodilation–triple therapy, when and why

M Cazzola, P Rogliani, R Laitano… - … Journal of Chronic …, 2022 - Taylor & Francis
… We strongly believe that the step-up approach from dual bronchodilation to triple therapy
exacerbation was lower if the contribution of bronchodilators was excluded, and in any case of …

[HTML][HTML] Impact of prior and concurrent medication on exacerbation risk with long-acting bronchodilators in chronic obstructive pulmonary disease: a post hoc analysis

I Naya, L Tombs, DA Lipson, I Boucot, C Compton - Respiratory research, 2019 - Springer
bronchodilator therapy in reducing … bronchodilator therapy where COPD exacerbation data
were available for 16 randomized control trials (RCTs; 18,224 patients), LAMA/LABA therapy

… broncho-obstructive syndrome in chronic heart failure of ischemic origin in combination with chronic obstructive pulmonary disease: simple randomized parallel group …

VV Evdokimov, AG Evdokimova… - …, 2023 - cardiosomatics.orscience.ru
… of long-acting bronchodilators. Therapy was well tolerated by all study groups, with no … and
losartan in basic therapy, while taking long-acting bronchodilators, improves the clinical and …

Efficacy and cardiovascular safety profile of dual bronchodilation therapy in chronic obstructive pulmonary disease: a bidimensional comparative analysis across fixed …

P Rogliani, MG Matera, BL Ritondo, I De Guido… - Pulmonary …, 2019 - Elsevier
… Despite dual bronchodilation therapy still represents the cornerstone therapy for most
patients with chronic obstructive pulmonary disease (COPD) [1], to date only few randomized …

[HTML][HTML] Comparative effectiveness of triple therapy versus dual bronchodilation in COPD

J Voorham, M Corradi, A Papi… - ERJ Open …, 2019 - Eur Respiratory Soc
… management in COPD are long-acting inhaled bronchodilators, either long-acting … acting
bronchodilator monotherapy, and inhaled corticosteroids (ICSs) can be added for triple therapy (…

… of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised controlled trial

ID Pavord, M Holliday, HK Reddel… - The Lancet …, 2020 - thelancet.com
… This study is a prespecified subgroup analysis of a 52-week, open-label, parallel-group
randomised controlled trial in patients with mild asthma, which compared as-needed salbutamol …

Efficacy and safety of inhaled glycopyrronium bromide in COPD: a randomized, parallel group, dose-ranging study (glimmer)

E Kerwin, G Feldman, J Pearle… - COPD: Journal of …, 2021 - Taylor & Francis
… is dosed BID it is likely that the bronchodilator efficacy of GB would be greater than tiotropium
… The bronchodilator effects of inhaled glycopyrronium have been studied using both once …