[HTML][HTML] Copper complexes as anticancer agents targeting topoisomerases I and II
C Molinaro, A Martoriati, L Pelinski, K Cailliau - Cancers, 2020 - mdpi.com
… of copper complexes exerts an effective inhibitory action on topoisomerases, which participate
in the regulation of DNA topology. Copper complexes … emerging cancer therapies opens …
in the regulation of DNA topology. Copper complexes … emerging cancer therapies opens …
From coins to cancer therapy: Gold, silver and copper complexes targeting human topoisomerases
J Ceramella, A Mariconda, D Iacopetta… - Bioorganic & Medicinal …, 2020 - Elsevier
… about the use of gold, silver and copper complexes as antitumor agents, highlighting their
… implicated in cancer onset and progression. The identification of lead complexes targeting …
… implicated in cancer onset and progression. The identification of lead complexes targeting …
Copper in tumors and the use of copper-based compounds in cancer treatment
DA da Silva, A De Luca, R Squitti, M Rongioletti… - Journal of inorganic …, 2022 - Elsevier
… used as a drug in cancer therapy with low adverse effects. … of copper in cancer, the effects
of copper-complexes on tumor cell death mechanisms, and point to the new copper complexes …
of copper-complexes on tumor cell death mechanisms, and point to the new copper complexes …
Copper-induced tumor cell death mechanisms and antitumor theragnostic applications of copper complexes
Y Jiang, Z Huo, X Qi, T Zuo, Z Wu - Nanomedicine, 2022 - Taylor & Francis
… With the advantages of Cu in cancer therapies, the potential biomedical applications of Cu
deserve to be widely exploited. Therefore, we subsequently highlighted the applications of Cu …
deserve to be widely exploited. Therefore, we subsequently highlighted the applications of Cu …
[HTML][HTML] Potential of copper and copper compounds for anticancer applications
P Ji, P Wang, H Chen, Y Xu, J Ge, Z Tian, Z Yan - Pharmaceuticals, 2023 - mdpi.com
… in cancer therapy and have become new hotspots in cancer … applications of novel copper
and copper compound-induced … in anticancer therapy, and its copper complexes can also …
and copper compound-induced … in anticancer therapy, and its copper complexes can also …
Biochemical pathways of copper complexes: Progress over the past 5 years
S Zehra, S Tabassum, F Arjmand - Drug Discovery Today, 2021 - Elsevier
… In cancer biology, copper acts as an antitumor agent by inhibiting cancer via multiple
pathways. Herein, we present an overview of advances in copper complexes as ‘lead’ antitumor …
pathways. Herein, we present an overview of advances in copper complexes as ‘lead’ antitumor …
[HTML][HTML] Metallo-drugs in cancer therapy: Past, present and future
… studies on platinum, copper and ruthenium metalo-drugs in cancer therapy, focusing on
past… In this review, we stopped only on platinum, copper and ruthenium complexes, presenting …
past… In this review, we stopped only on platinum, copper and ruthenium complexes, presenting …
[HTML][HTML] Modulation of intracellular copper levels as the mechanism of action of anticancer copper complexes: Clinical relevance
… Systemic Changes in Cu Homeostasis of Cancer Patients Since copper plays an important
… are significant differences in Cu levels in cancer patients in comparison with healthy cohorts, …
… are significant differences in Cu levels in cancer patients in comparison with healthy cohorts, …
Dithiocarbazate-copper complexes for bioimaging and treatment of pancreatic cancer
Y Gou, MR Chen, S Li, JG Deng, J Li… - Journal of Medicinal …, 2021 - ACS Publications
… cancer cells, such as ferroptosis, warrant further investigation. Here, we synthesized three
fluorescent copper complexes … } to evaluate the ability of antipancreatic cancer. Notably, the …
fluorescent copper complexes … } to evaluate the ability of antipancreatic cancer. Notably, the …
In vitro and in vivo anticancer activity of tridentate thiosemicarbazone copper complexes: Unravelling an unexplored pharmacological target
M Carcelli, M Tegoni, J Bartoli, C Marzano… - European Journal of …, 2020 - Elsevier
… (C) LoVo cancer cells were incubated with 1 μM of copper complexes for 24 h and samples
were processed for sub-fractions preparation as reported in the Experimental Section. The …
were processed for sub-fractions preparation as reported in the Experimental Section. The …
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