Copper‐mediated nucleophilic radiofluorination of [18F]βCFT for positron emission tomography imaging of dopamine transporter

HM Yu, CY Li, SW Liu, CH Yang… - Journal of Labelled …, 2021 - Wiley Online Library
… Spealman et al. showed that 2-β-carbomethoxy-3-β-(4-fluorophenyl)tropane (β-CFT, WIN …
binding ratio of β-CFT was measured with the 3 H-labeled β-CFT. [ 3 H]β-CFT was considered …

[HTML][HTML] Efficacy of 11C-2β-carbomethoxy--(4-fluorophenyl) tropane positron emission tomography combined with 18F-fluorodeoxyglucose positron emission …

L Jiang, X Wang, P Li, Z Feng, X Shi, H Shao - Medicine, 2020 - journals.lww.com
… The purpose of this study is to evaluate the efficacy of 11 C-CFT PET combined with 18 F-…
C-CFT PET combined with 18 F-FDG PET. We will exclude the combination of 11 C-CFT PET, …

… emission tomography/computed tomography dual imaging using 18-fluorine flurodeoxyglucose and 11C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane for …

X Li, Q Zhang, Y Qin, Y Li, N Mutaerbieke, X Zhao… - Medicine, 2020 - journals.lww.com
… The 11 C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane ( 11 C-CFT) is a cocaine
derivative with a high affinity with DAT on the presynaptic membrane and reflects the function …

Kinetic modeling with different reference tissues improves 11C-CFT total-body PET/CT quantification studies in parkinsonism

M Xin, Y Wang, C Zhang, Y Zhou, J Liu - 2023 - Soc Nuclear Med
… -carbomethoxy-3-beta-(4-fluorophenyl)tropane ( 11 C-CFT), a … of total-body 11 C-CFT PET/CT
in studies of parkinsonism. … gold standard in quantifying 11 C-CFT binding, two other DAT-…

Synthesis of dopamine transporter imaging agent 11C- β- CFT and its application in the diagnosis of Parkinson's disease

W Hui, LIU Ziyu, BAI Xia, BAO Baoliang, HE Yulin - 分子影像学杂志, 2023 - j-fzyx.com
… -2β-carbomethoxy--(4-flurophenyl) tropanel( 11 C-β-CFT) … online and the precursor
2β-carbomethoxy--(4-flurophenyl) … and the product 11 C-β-CFT was eluted from the C18 column …

Impact of TOF on Brain PET With Short-Lived 11C-Labeled Tracers Among Suspected Patients With AD/PD: Using Hybrid PET/MRI

DDN Wimalarathne, W Ruan, X Sun, F Liu, Y Gai… - Frontiers in …, 2022 - frontiersin.org
… -ß-carbomethoxy-3-b-(4-fluorophenyl) tropane ( 11 C-CFT) (8). In the patients with PD, the
DATs level will change, and the PET images with 11 C-CFT … control of 11 C-CFT and 11 C-PiB …

Hypnic headache with dopaminergic neuron dysfunction: new insight from a rare case

Y Zhang, C Wang, Y Chen, R Wang, Y Lian - Pain Medicine, 2019 - academic.oup.com
… Head 11 C-CFT PET/CT imaging showed a decrease in 11 C-CFT uptake in … -CFT PET/CT
imaging was utilized to assess the dopamine transporter functions in the brain. The 11 C-CFT

Characteristics and influencing factors of 11C-CFT PET imaging in patients with early and late onset Parkinson's disease

F Kangli, Z Hongguang, L Yinghua, D Xiaoxiao… - Frontiers in …, 2023 - frontiersin.org
… DAT-PET imaging is based on the principle that 11 C-methyl-N-2β-carbomethoxy--(4-fluorophenyl)-tropanel
( 11 C-CFT) tracers specifically bind to striatal DAT to visualize the …

Rapid eye movement sleep behavior disorder in tremor and non-tremor Parkinson's disease show different patterns of 11C-CFT and 18F-FDG PET/CT imaging

M Xin - 2020 - Soc Nuclear Med
… C-CFT uptake values in caudate nucleus, anterior putamen and posterior putamen as well
… Results: Caudate dopamine depletion of the 11 C-CFT PET/CT imaging in PD patients with …

Increased anteroventral striatal dopamine transporter and motor recovery after subthalamic deep brain stimulation in Parkinson's disease

T Nozaki, K Sugiyama, T Asakawa, H Namba… - Journal of …, 2021 - thejns.org
… [11C]2β-carbomethoxy--(4-fluorophenyl)tropane ([11C]CFT). … scanned twice with [11C]CFT
PET just before and 1 year … ]CFT binding with the percentage change in [11C]CFT binding …