Tachykinins and the potential causal factors for post-COVID-19 condition

SJ Janket, DD Fraser, AE Baird, F Tamimi… - The Lancet …, 2023 - thelancet.com
tachykinins and propose a putative pathogenic mechanism. The antagonism of tachykinins
receptors … Notably, both bradykinin and substance P increase vascular permeability and pain …

Regulatory peptides in asthma

K Kaczyńska, D Zając, P Wojciechowski… - International Journal of …, 2021 - mdpi.com
… the regulation of vascular tone… receptors, limits the recruitment of neutrophils in rat airways
[101]. There is also strong evidence indicating the role of tachykinins and tachykinin receptors

The role of transient receptor potential vanilloid 1 in common diseases of the digestive tract and the cardiovascular and respiratory system

Q Du, Q Liao, C Chen, X Yang, R Xie, J Xu - Frontiers in Physiology, 2019 - frontiersin.org
… only TRPV1 receptors. The cardiac sympathetic afferent terminals expressing TRPV1 also
express many other sensory receptors, such as tachykinins and purinergic receptors. RTX …

Hemokinin-1 induces transcriptomic alterations in pain-related signaling processes in rat primary sensory neurons independent of NK1 tachykinin receptor activation

K Takács-Lovász, T Aczél, É Borbély… - Frontiers in Molecular …, 2023 - frontiersin.org
… A regulatory subunit binding, and thyroid hormone receptor … G protein-coupled receptor
signaling pathway, positive regulation of T … , positive regulation of leukocyte adhesion to vascular

Neurogenic Tachykinin Mechanisms in Experimental Nephritis of Rats: PO2135

K Rodionova, T Ditting, G Tiegs… - Journal of the …, 2020 - journals.lww.com
… signal regulatory protein alpha (SIRPα), a substrate for tyrosine phosphatases, in cardiac
muscle … signaling via interactions with the insulin-like growth factor-1 receptor (IGF-1R) in CKD. …

Neurological regulation of the bone marrow niche

F Aerts-Kaya, B Ulum, A Mammadova, S Köse… - Cell Biology and …, 2020 - Springer
… P (SP) and Tachykinins, as well as neurotrophins and … Regulation of vascular integrity was
shown to be mediated by interactions with NPY-Y2 and Y5 receptors, and Y2 and Y5 receptor

Neurokinin receptor antagonism: a patent review (2014-present)

M Muñoz, R Coveñas - Expert Opinion on Therapeutic Patents, 2020 - Taylor & Francis
… As tachykinin peptides and their receptors are involved in many physiological and … (from
2014 to present) the patents in which the use of NK receptor antagonists has been reported. …

[HTML][HTML] … in dry eye disease is regulated by substance P/neurokinin-1 receptor system through controlling expression of vascular endothelial growth factor receptor 3

SJ Lee, ST Im, J Wu, CS Cho, DH Jo, Y Chen, R Dana… - The ocular …, 2021 - Elsevier
… and expression of vascular endothelial growth factor (VEGF) receptor 3 stimulated by SP
in … VEGF-C, VEGF-D, and VEGF receptor 3 in the corneal and conjunctival tissues of DED. …

Input-output signal processing plasticity of vagal motor neurons in response to cardiac ischemic injury

J Gorky, A Moss, M Balycheva, R Vadigepalli… - Iscience, 2021 - cell.com
… intracardiac neuron effectors like ANP and tachykinins as discussed later. These … receptors.
It also has a clear upregulation of the beta-1 adrenergic receptor, better known for its cardiac

[HTML][HTML] Neurokinin-1 receptor as a potential drug target for COVID-19 treatment

R Mehboob - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… Here, we propose that SP via its tachykinin receptor, NK-1R is responsible for inflammation
… widely distributed through cardiac conduction system and involved in its regulation at various …