… silico assessment of the proliferative and angiogenic potential of Substance K: Interaction of Substance K between the Neurokinin-1, Neurokinin-2, and Tie-2 receptor …

E Simsek, ET Akcit, O Kocak, K Yildirim… - Chemical Biology …, 2024 - pubs.thesciencein.org
… angiogenesis, the effect of substance K on vascular endothelial cells in vitro should also be
… have agonist effects on their receptors. Tachykinin receptors are expressed in many cancer …

Neuropeptide signalling systems–an underexplored target for venom drug discovery

HC Mendel, Q Kaas, M Muttenthaler - Biochemical pharmacology, 2020 - Elsevier
… in the vascular system plays a minor role in the regulation of blood … receptors in another
phylum. For example, vertebrate substance P is able to activate a Drosophila tachykinin receptor

Peptidergic systems and cancer: Focus on tachykinin and calcitonin/calcitonin gene-related peptide families

ML Sánchez, FD Rodríguez, R Coveñas - Cancers, 2023 - mdpi.com
… of vascular endothelial cadherin and dissociation of vascular endothelial cadherin/vascular
endothelial growth factor receptor 2/… of vascular endothelial growth factor receptor 2 and the …

IGFs potentiate TAC3-induced SLα expression via upregulation of TACR3 expression in grass carp pituitary cells

G Hu, M He, WKW Ko, C Ye, Q Hu, AOL Wong - Cells, 2019 - mdpi.com
… the tachykinin 3 (TAC3)/tachykinin receptor 3 (TACR3) systems have been confirmed to play
an important role in the regulation of … The cardiovascular functions of TACR3 has also been …

Parvalbumin interneuron activity drives fast inhibition-induced vasoconstriction followed by slow substance P-mediated vasodilation

TT Vo, GH Im, K Han, M Suh… - Proceedings of the …, 2023 - National Acad Sciences
… signaling is important for vascular regulation during sleep. Our … the role of PV neurons in
controlling the vascular response. … selective SP receptor, neurokinin 1 (or tachykinin) receptor (…

Drosophila tachykininergic neurons modulate the activity of two groups of receptor-expressing neurons to regulate aggressive tone

MP Wohl, J Liu, K Asahina - Journal of Neuroscience, 2023 - Soc Neuroscience
… that label tachykinin receptor-expressing neurons to probe how tachykinin modulates …
neurons, each expressing a different Drosophila tachykinin receptor (TkR86C or TkR99D). …

Role of neuroimmune circuits and pruritus in psoriasis

MT Ayasse, J Buddenkotte, M Alam… - Experimental …, 2020 - Wiley Online Library
… , 139 SP and its cognitive receptor neurokinin/tachykinin receptor 1 are additionally increased
in … The vascular growth function of VIP might be dependent on its regulation of vascular

The Role of Substance P in the Regulation of Bone and Cartilage Metabolic Activity

MH Zheng, SK Shan, LQ Yuan - … Peptides in the Control of Cell …, 2021 - books.google.com
… as the tachykinin 1 receptor, TACR1) (6) has the highest affinity for SP and is the main receptor
of … (52) showed that the NK-R1 antagonist LY303870 partially reversed the vascular and …

Molecularly defined circuits for cardiovascular and cardiopulmonary control

A Veerakumar, AR Yung, Y Liu, MA Krasnow - Nature, 2022 - nature.com
receptors such as thyrotropin-releasing hormone receptor (Trhr), tachykinin receptor 3 (Tacr3),
and melanocortin receptor 4 (… receptor (Ghsr), serotonin receptor 3B (Htr3b), somatostatin …

The role of substance P in the regulation of bone and cartilage metabolic activity

FXZ Li, F Xu, X Lin, F Wu, JY Zhong, Y Wang… - Frontiers in …, 2020 - frontiersin.org
… as the tachykinin 1 receptor, TACR1) (6) has the highest affinity for SP and is the main receptor
of … (52) showed that the NK-R1 antagonist LY303870 partially reversed the vascular and …