Small-cell lung cancer

CM Rudin, E Brambilla, C Faivre-Finn… - Nature Reviews Disease …, 2021 - nature.com
Lung cancer is the leading cause of cancer mortality worldwide… Lung cancer, including all
histological subtypes, is more … As with lung cancer in general, SCLC is most prevalent in men …

Immunotherapeutic approaches for small-cell lung cancer

WT Iams, J Porter, L Horn - Nature Reviews Clinical Oncology, 2020 - nature.com
… Various tumour-based and/or blood-based assays have been evaluated for their ability to
predict clinical benefit from immune-checkpoint inhibitors in patients with small-cell lung cancer

Update 2020: management of non-small cell lung cancer

M Alexander, SY Kim, H Cheng - Lung, 2020 - Springer
… in the management of non-small cell lung cancer (NSCLC) with remarkable progresses in …
improved patient outcomes. This review will address updates in lung cancer screening, liquid …

Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients

XC Zhang, J Wang, GG Shao, Q Wang, X Qu… - Nature …, 2019 - nature.com
patients. Here we report an extensive molecular and immune profiling study of 245 … patients
with non-small cell lung cancer. Tumor-infiltrating lymphocyte estimated using immune cell

Immune cell composition in human non-small cell lung cancer

B Stankovic, HAK Bjørhovde, R Skarshaug… - Frontiers in …, 2019 - frontiersin.org
Lung cancer is the leading cause of cancer-related death worldwide with a high annual …
Non-small cell lung cancer (NSCLC) is the most common type of lung cancers, representing ~90…

Toward personalized treatment approaches for non-small-cell lung cancer

M Wang, RS Herbst, C Boshoff - Nature medicine, 2021 - nature.com
lung cancer is the most common cause of cancer-related deaths. Molecular targeted therapies
and immunotherapies for non-small-cell lung cancer … for clear-cut patient stratification, and …

Current diagnosis and management of small-cell lung cancer

S Wang, S Zimmermann, K Parikh, AS Mansfield… - Mayo Clinic …, 2019 - Elsevier
… Small-cell lung cancer (SCLC) is an aggressive disease with distinct pathological, clinical,
and molecular characteristics from non–small-cell lung cancer. SCLC has high metastatic …

Emerging therapies for small cell lung cancer

S Yang, Z Zhang, Q Wang - Journal of hematology & oncology, 2019 - Springer
… in extensive disease small-cell lung cancer was performed in 2017. In this study, 30
patients in the expansion phase received treatment, and 20 patients reported over 1 treatment-…

Comprehensive T cell repertoire characterization of non-small cell lung cancer

A Reuben, J Zhang, SH Chiou, RM Gittelman… - Nature …, 2020 - nature.com
… T cell clonality is associated with CD8 T cells To study the attributes of the T cell repertoire in
localized lung cancers, … 236 resected tumors from treatment-naïve NSCLC patients 16,17 . T …

Update of incidence, prevalence, survival, and initial treatment in patients with non–small cell lung cancer in the US

AK Ganti, AB Klein, I Cotarla, B Seal, E Chou - JAMA oncology, 2021 - jamanetwork.com
… of elderly patients with non-small-cell lung cancer.  … B patients receiving low-dose CT scans
for lung cancer screening (… management of elderly patients with non-small-cell lung cancer.  …