Skeletal muscle: A review of molecular structure and function, in health and disease

K Mukund, S Subramaniam - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
diseases affecting muscle (italicized in text). Finally, in Section 13, we summarize and highlight
common molecular mechanisms … of cellular components and molecular mechanisms for …

[HTML][HTML] Fibroblasts: Origins, definitions, and functions in health and disease

MV Plikus, X Wang, S Sinha, E Forte, SM Thompson… - Cell, 2021 - cell.com
… We propose that fibroblasts are uniquely poised for tissue repair by easily reentering the
cell cycle and exhibiting a reversible plasticity in phenotype and cell fate. These properties, …

[HTML][HTML] Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease

T Guo, D Zhang, Y Zeng, TY Huang, H Xu… - Molecular …, 2020 - Springer
… contributions to various molecular and cellular pathways in AD pathogenesis. Herein, we
review recent progress with respect to Aβ- and tau-associated mechanisms, and discuss glial …

Mitocellular communication: Shaping health and disease

A Mottis, S Herzig, J Auwerx - Science, 2019 - science.org
… to stress is key to leveraging mitochondrial communication to maintain health at the cellular
or organismal level. The cellular response to mitochondrial dysfunction ranges from up-…

[HTML][HTML] Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

R Sartori, V Romanello, M Sandri - Nature communications, 2021 - nature.com
… Understanding the mechanisms that control muscle mass will provide therapeutic targets
for the treatment of muscle loss in inherited and non-hereditary diseases and for the …

[HTML][HTML] Hallmarks of endothelial cell metabolism in health and disease

X Li, X Sun, P Carmeliet - Cell metabolism, 2019 - cell.com
In 2009, it was postulated that endothelial cells (ECs) would only be able to execute the orders
of growth factors if these cells would accordingly adapt their metabolism. Ten years later, …

Cellular senescence as a mechanism and target in chronic lung diseases

PJ Barnes, J Baker, LE Donnelly - American journal of respiratory …, 2019 - atsjournals.org
… comorbidities of COPD and other lung diseases. Understanding the mechanisms of cellular
senescence may result in new treatments for chronic lung disease, either by inhibiting PI3K–…

Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications

R Weiskirchen, S Weiskirchen, F Tacke - Molecular aspects of medicine, 2019 - Elsevier
… or Gli1 positive mesenchymal stem cell-like cells, to a transition of various cell types into …
principles of fibrogenic molecular signals and cellular mechanisms in various organs - such …

[HTML][HTML] Nitric oxide signaling in health and disease

JO Lundberg, E Weitzberg - Cell, 2022 - cell.com
The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

[HTML][HTML] Molecular mechanisms of cell death in neurological diseases

D Moujalled, A Strasser, JR Liddell - Cell Death & Differentiation, 2021 - nature.com
diseases or tumorigenesis in the brain. We also discuss the interplay between distinct cell
death signalling cascades and disease … key players in the cell death signalling pathways that …