… Sex-chromosome dosage (SCD) effects on human gene expression are central to the
biology of sex differences and sex-chromosome aneuploidy syndromes but are challenging to …

… 21 and is the most common chromosomal aneuploidy present in live births, … chromosome
21 but also across the entire genome (4). Global or region-specific DNA CpG hypermethylation …

… to aberrant methylation patterns in the … methylation patterns in the chorionic villi in cases
of early pregnancy loss. Comparing the global DNA methylation and LINE-1 methylation levels …

… chromosome aneuploidy would have an effect on epigenetic patterns, possibly traceable in
the methylation … extra X chromosome on the genome-wide DNA methylation and expression …

… The impact of aneuploidy and polyploidy on cellular fitness … the proliferative effects of
chromosomal aneuploidies in human renal … facilitated most chromosomal arm-level aneuploidies. …

… remodeling of DNA methylation patterns, which involves not only chromosome 21 but is …
Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from down syndrome …

… from an extra copy of human chromosome 21 (HSA21). DS is the most common genetic
cause of intellectual disability and also the most common chromosomal aneuploidy in live-births, …

… regression analyses to identify methylation patterns of CpG sites … represented as featured
DNA methylation patterns. In order … CIN based on DNA methylation patterns of genes using the …

… Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down
syndrome and mouse models. Genome Biol [Internet]. 2015 Nov 25 [cited 2023 Feb 21];16(1):1…

… focus on DNA methylation 89 and … chromosomes. They bind proteins belonging to the
shelterin complex 137 (TRF1, TRF2, POT1, TIN2, TPP1, and Rap1), and help protect chromosome …