… subsequent growth in cases of leptomeningeal metastases. … of clinically relevant mutations
in the brain metastases that … introduction of the idea that brain metastases may not share the …

… , a number of clinical trials designed to … clinical management of patients with brain metastases,
with an emphasis on recent advances in prognostication, genomics, surgery, whole-brain …

… Several factors influence the development of brain metastasis. Karnofsky performance scale
… useful in estimating the prognosis for patients undergoing treatment of brain metastases. …

… Thus, interactions between cancer cells and these brain-specific cell types are unique to
brain metastases. In the case of the leptomeninges, the pia and arachnoid contain circulating …

Brain metastasis (BM), the most common adult brain tumor, develops in 20% to 40% of
patients with late‐stage cancer and traditionally are associated with a poor prognosis. The …

… The prevalence of brain metastases is increasing due to … of brain metastases is to achieve
local control of the metastatic … with brain metastases based on the evidence from clinical trials …

… Previous prognostic factors in brain metastases included clinical variables only such as
patient age, performance status, extracranial metastases and number of brain metastases. …

… and their primary tumors [26,27,28], no significant differences were observed in mutation
profiles between a case series of breast cancer brain metastases and their primary lesions [29]. …

… of brain metastases in the United States have varied, but it is likely that 70 000-400 000 new
cases of brain metastases … tumors will develop brain metastases over their clinical course. …

… Brain metastases from breast cancer (BCBM) constitute the second most common cause
of brain metastasis (BM), and the incidence of these frequently lethal lesions is currently …