Ischemia-reperfusion injury in marginal liver grafts and the role of hypothermic machine perfusion: molecular mechanisms and clinical implications

Z Czigany, I Lurje, M Schmelzle, W Schöning… - Journal of Clinical …, 2020 - mdpi.com
… The clinical effects of IRI can manifest as a broad spectrum of short-term and long-term
complications, resulting in an overall inferior patient survival [5,6]. IRI-induced complications …

[HTML][HTML] Ischemia-free liver transplantation improves the prognosis of recipients using functionally marginal liver grafts

S Wang, X Lin, Y Tang, Y Liang, M Zhang… - Clinical and …, 2024 - ncbi.nlm.nih.gov
… This study aimed to clarify the poor outcomes of functionally marginal liver grafts (FMLs) and
provide evidence for the improvement of ischemia-free liver transplantation (IFLT) after FML …

Multinational analysis of marginal liver grafts based on the Eurotransplant extended donor criteria

S Moosburner, MS Patel, BK Wang, J Prasadh… - Annals of …, 2024 - journals.lww.com
… This study evaluates the outcome of over 70,000 transplants, analyzing the impact of marginal
liver grafts based on the “Eurotransplant Extended Donor Criteria”, comparing a German …

Assessment of trends in transplantation of liver grafts from older donors and outcomes in recipients of liver grafts from older donors, 2003-2016

CE Haugen, CM Holscher, X Luo, MG Bowring… - JAMA …, 2019 - jamanetwork.com
Importance In light of the growing population of older adults in the United States, older donors
(aged ≥70 years) represent an expansion of the donor pool; however, their organs are …

[PDF][PDF] Prognostic Factors in Liver Transplant with Marginal Grafts-Review of the Literature

M Serban, I Balescu, S Petrea, B Gaspar… - Chirurgia (Bucharest …, 2024 - revistachirurgia.ro
… Goldaracena et al. concluded that extremely marginal liver grafts (with a score ≥ 3 ) could
… Extremely marginal liver grafts from deceased donors have outcome similar to ideal grafts. …

[HTML][HTML] A marginal liver graft with hyperbilirubinemia transplanted successfully by ischemia-free liver transplantation

C Huang, Z Chen, T Wang, X He… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
The shortage of transplant organs remains a serious issue worldwide, and using liver grafts
from extended criteria donors could expand the donor pool. Extended criteria donor liver …

Steatosis in liver transplantation: current limitations and future strategies

I Linares, M Hamar, N Selzner, M Selzner - Transplantation, 2019 - journals.lww.com
… persufflation has already moved into the clinical application. The first human trial was
reported in 2008, where VSOP was applied to rescue marginal liver grafts with less than 20% …

The Graz Liver Allocation Strategy—Impact of Extended Criteria Grafts on Outcome Considering Immunological Aspects

J Kahn, G Pregartner, A Avian, D Kniepeiss… - Frontiers in …, 2020 - frontiersin.org
… Thus, this study was designed to assess the impact of EDCs on outcome including … The
impact of EDCs on outcome after LT was assessed retrospectively using both MedOcs and ENIS (…

Ex vivo machine perfusion: current applications and future directions in liver transplantation

J Michelotto, JMGV Gassner, S Moosburner… - … archives of surgery, 2021 - Springer
Marginal liver grafts may be obtained from elderly donors, those with clinical factors
predisposing them to hepatic steatosis, or from donation after circulatory death (DCD), compared …

Ischemia-free liver transplantation improves the prognosis of recipients using Functioned Marginal Liver grafts

S Wang, X Lin, Y Tang, Y Liang, M Zhang, Z Xie… - Clinical and molecular …, 2024 - e-cmh.org
… This study aimed to clarify the poor outcomes of functioned marginal liver grafts (FMLs)
and … the negative impact of FMLs in liver transplantation patients. We compared the clinical