The effect of nicorandil in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a systematic review and meta-analysis

Z Ji, R Zhang, W Lu, G Ma, Y Qu - Irish Journal of Medical Science (1971-), 2020 - Springer
… In rat coronary microembolization (CME) model, nicorandil may play anti-inflammation,
antioxidant, and anti-apoptosis roles through activating the Nrf2/ho-1 signaling pathway to protect …

Nicorandil protects against coronary microembolization-induced myocardial injury by suppressing cardiomyocyte pyroptosis via the AMPK/TXNIP/NLRP3 signaling …

Y Liu, J Shu, T Liu, J Xie, T Li, H Li, L Li - European journal of pharmacology, 2022 - Elsevier
… , but the cardioprotective effects of nicorandil beyond anti-… present study investigated the
effect of nicorandil on CME-… indicated that the protective effects of nicorandil in CME likely …

Efficacy of nicorandil on the prevention of contrast-induced nephropathy in patients with coronary heart disease undergoing percutaneous coronary intervention

X Zhang, S Yang, P Zhang, N Fu - Coronary Artery Disease, 2020 - journals.lww.com
… study was to explore the effect of nicorandil on the incidence of contrast-induced nephropathy
in patients with coronary heart disease undergoing percutaneous coronary intervention. …

Nicorandil inhibits cardiomyocyte apoptosis and improves cardiac function by suppressing the HtrA2/XIAP/PARP signaling after coronary microembolization in rats

J Zheng, M Long, Z Qin, F Wang… - Pharmacology …, 2021 - Wiley Online Library
… the deterioration of cardiac function after coronary microembolization (CME). Nicorandil (NIC) …
Therefore, we analyzed the impact of NIC on cardiac function in rats subjected to CME and …

Effects of nicorandil administration on infarct size in patients with ST‐segment–elevation myocardial infarction undergoing primary percutaneous coronary intervention …

G Qian, Y Zhang, W Dong, ZC Jiang, T Li… - Journal of the …, 2022 - Am Heart Assoc
… through reducing area of microcirculatory occlusion, improving myocardial ischemic
preconditioning, reducing microvascular spasm, inhibition of oxidative stress and microembolization

Effects of Nicorandil on All-Cause Mortality and Cardiac Events in CAD Patients Receiving PCI A Systematic Review and Meta-Analysis

X Zhang, Q Yu, X Yao, G Liu, J Li, L Du - International Heart Journal, 2019 - jstage.jst.go.jp
… PCI can also lead to abnormal microvascular vasomotility and distal coronary
microembolization of atheromatous and thrombotic debris and may cause aggravation of microcirculatory …

[HTML][HTML] Effects of intracoronary injection of nicorandil and tirofiban on myocardial perfusion and short-term prognosis in elderly patients with acute ST-segment …

G Chen, H Wang, J Zou, X Yuan - World Journal of Emergency …, 2020 - ncbi.nlm.nih.gov
… investigated the effects of combined treatment with nicorandil and … that the intra-coronary
injection of nicorandil and tirofiban is … microcirculation and subsequent microembolization are …

Effects of nicorandil on systemic inflammation and oxidative stress induced by percutaneous coronary intervention in patients with coronary heart disease

Y Zong, J Li, X Xu, X Xu - Journal of International Medical …, 2021 - journals.sagepub.com
… the effects of a bolus intracoronary injection of nicorandil on systemic inflammation and
oxidative stress induced by percutaneous coronary intervention (PCI) in patients with coronary

[Retracted] Protective Effect of Nicorandil on Cardiac Microvascular Injury: Role of Mitochondrial Integrity

X Jiang, D Wu, Z Jiang, W Ling… - Oxidative Medicine and …, 2021 - Wiley Online Library
… [99] constructed a coronary microembolization (CME) rat model and demonstrated that
nicorandil inhibited myocardial inflammation, alleviated myocardial injury, and improved cardiac

Nicorandil for periprocedural myocardial injury in elective percutaneous coronary intervention: a meta-analysis of 10 randomized controlled trials

B Yi, J Luo, Y Jiang, S Mo, X Xiao, X Chen… - Angiology, 2020 - journals.sagepub.com
… of nicorandil in percutaneous coronary intervention (PCI) are conflicting. We sought to evaluate
the effects of nicorandil on … Eligible studies that reported the effect of nicorandil on PMI in …