Effects of altered excitation-inhibition balance on decision making in a cortical circuit model

NH Lam, T Borduqui, J Hallak, A Roque… - Journal of …, 2022 - Soc Neuroscience
… However, the circuit mechanisms by which E/I imbalance leads to … in decision-making have
remained unclear. We used a computational model of decision-making in cortical circuits to …

A cortical circuit mechanism for structural knowledge-based flexible sensorimotor decision-making

Y Liu, Y Xin, N Xu - Neuron, 2021 - cell.com
… -specific optogenetics, we found that auditory cortex (ACx) neurons encoded the hidden
task … cortical circuit mechanism underlying structural knowledge-based flexible decision-making. …

Striatal circuits for reward learning and decision-making

J Cox, IB Witten - Nature Reviews Neuroscience, 2019 - nature.com
… striatal circuit, we briefly review classic ideas about their role in learning and decision-making, …
receive inputs from the prefrontal cortex, could oppositely influence value-based decision-…

Amygdala-cortical collaboration in reward learning and decision making

KM Wassum - Elife, 2022 - elifesciences.org
… using reward memories to guide decision making. The BLA→lOFC … circuit architecture for
reward learning and decision making and … for both adaptive and maladaptive decision making. …

An integrated model of action selection: distinct modes of cortical control of striatal decision making

MJ Sharpe, T Stalnaker, NW Schuck… - Annual review of …, 2019 - annualreviews.org
… control from the prelimbic and orbitofrontal cortices over striatal activity through distinct
thalamostriatal circuits. We suggest that the prelimbic cortex exerts direct influence over medium …

[HTML][HTML] Fast and slow contributions to decision-making in corticostriatal circuits

ZZ Balewski, EB Knudsen, JD Wallis - Neuron, 2022 - cell.com
… nucleus and orbitofrontal cortex while animals made value-guided decisions. Using population-…
In contrast, the dynamics in orbitofrontal cortex were more consistent with a deliberative …

Anxiety and stress alter decision-making dynamics and causal amygdala-dorsolateral prefrontal cortex circuits during emotion regulation in children

SL Warren, Y Zhang, K Duberg, P Mistry, W Cai… - Biological …, 2020 - Elsevier
… To investigate the role of causal amygdala-DLPFC circuits in … would be sensitive to decision
making and evaluation of … “hijacking” a key cortical circuit involved in cognitive control. If it …

Prefrontal–amygdala circuits in social decision-making

P Gangopadhyay, M Chawla, O Dal Monte… - Nature …, 2021 - nature.com
… 1c, 2c, 3c and 4c–e) to discuss the neurobiological substrates in these broadly defined
aspects of social decision-making. We focus on the amygdala and prefrontal cortex (PFC) …

Hierarchical reasoning by neural circuits in the frontal cortex

M Sarafyazd, M Jazayeri - Science, 2019 - science.org
decisions about unreliable stimuli (middle). In nonhuman primates, this cognitive capacity was
supported by circuit-level interactions in the frontal cortex … implemented by cortical circuits. …

Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning

F Najafi, GF Elsayed, R Cao, E Pnevmatikakis… - Neuron, 2020 - cell.com
cortex: … decision circuits and, hence, the validity of decision-making models are unknown.
We simultaneously measured excitatory and inhibitory neurons in the posterior parietal cortex