Biosystem design of Corynebacterium glutamicum for bioproduction

J Zha, Z Zhao, Z Xiao, T Eng, A Mukhopadhyay… - Current Opinion in …, 2023 - Elsevier
glutamicum is an excellent host to synthesize various organic acids (ie lactate, succinate,
pyruvate, and α-ketoglutarate) 15, 16• and short-chain alcohols (Table 1) [17]. …

Microbial synthesis of the type I polyketide 6-methylsalicylate with Corynebacterium glutamicum

N Kallscheuer, H Kage, L Milke, M Nett… - Applied microbiology …, 2019 - Springer
glutamicum, which enabled plant polyphenol synthesis with this bacterium (Kallscheuer et
al… glutamicum as a promising microbial host for polyketide production as we could functionally …

[HTML][HTML] Metabolic engineering of Corynebacterium glutamicum S9114 based on whole-genome sequencing for efficient N-acetylglucosamine synthesis

C Deng, X Lv, Y Liu, J Li, W Lu, G Du, L Liu - Synthetic and Systems …, 2019 - Elsevier
synthesis. Compared with the former two, the production method via microbial synthesis has
… , we selected an alternative host bacterium, Corynebacterium glutamicum, and engineered …

[HTML][HTML] Metabolic Engineering of Corynebacterium glutamicum for Production of UDP-N-Acetylglucosamine

R Gauttam, CK Desiderato, D Radoš, H Link… - … in Bioengineering and …, 2021 - frontiersin.org
… However, chemical synthesis is complex and non-economical, and in vitro synthesis
requires … , Gram-positive soil bacterium Corynebacterium glutamicum as a host for UDP-GlcNAc …

[HTML][HTML] … expression system with high compatibility between expression elements and an optimized host for endoxylanase production in Corynebacterium glutamicum

W Zhang, Y Yang, X Liu, C Liu, Z Bai - Microbial Cell Factories, 2019 - Springer
… strain always function well in the original host. In the present study, to … in Corynebacterium
glutamicum CGMCC1.15647 with its native expression elements, approaches to reduce host

Engineering of the Translesion DNA Synthesis Pathway Enables Controllable C-to-G and C-to-A Base Editing in Corynebacterium glutamicum

Y Wang, D Zhao, L Sun, J Wang, L Fan… - ACS Synthetic …, 2022 - ACS Publications
… Here, we discovered that the DNA polymerase V-mediated translesion DNA synthesis (TLS) …
main product of the GBE in Corynebacterium glutamicum and subsequent gene inactivation …

Ecofriendly Synthesis of l-Carnosine in Metabolically Engineered Corynebacterium glutamicum by Reinforcing Precursor Accumulation

M Kim, YJ Ko, DW Jeong, WY Jeong… - ACS Synthetic …, 2021 - ACS Publications
synthesis, and as an alternative to this method, we newly developed engineered
Corynebacterium glutamicumglutamicum ATCC 13032 was used as the host strain for l-carnosine …

Biosynthesis of chondroitin in engineered Corynebacterium glutamicum

F Cheng, S Luozhong, H Yu, Z Guo - Journal of Microbiology and …, 2019 - koreascience.kr
… CgkfoC and CgkfoA genes with host codon preference were synthesized and … host,
intracellular chondroitin titer increased from 0.25 to 0.88 g/l compared with that in a wild-type host. …

[HTML][HTML] … of the character impact compound raspberry ketone and additional flavoring phenylbutanoids of biotechnological interest with Corynebacterium glutamicum

L Milke, M Mutz, J Marienhagen - Microbial cell factories, 2020 - Springer
… In this study, Corynebacterium glutamicum was engineered for the microbial synthesis of the
… cerevisiae for microbial RK synthesis demonstrated that both hosts provide an endogenous …

[HTML][HTML] Metabolic engineering of Corynebacterium glutamicum for producing branched chain amino acids

S Yu, B Zheng, Z Chen, YX Huo - Microbial Cell Factories, 2021 - Springer
glutamicum has served as a host for producing industrial-scale medicines, as well as bulk
and … Corynebacterium glutamicum XV has evolved more pyruvate for l-valine synthesis and …