Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons
D Beck, M Ben Maamar, MK Skinner - Epigenetics, 2022 - Taylor & Francis
… in DNA methylation methods involves CpG density. The current study was designed to
investigate the CpG density … and correlate this to various DNA methylation analysis data sets. The …
investigate the CpG density … and correlate this to various DNA methylation analysis data sets. The …
[HTML][HTML] Local CpG density affects the trajectory and variance of age-associated DNA methylation changes
… We analyze longitudinal human DNA methylation trajectories at 345,895 CpGs from 600 …
epigenetic changes at individual CpGs. We show that changes in methylation with age occur at …
epigenetic changes at individual CpGs. We show that changes in methylation with age occur at …
CG dinucleotides enhance promoter activity independent of DNA methylation
… with our previous findings that CpGs indeed protect against DNA methylation. These CpG-poor …
We previously argued that DNA methylation is generally repressive at high CpG density (…
We previously argued that DNA methylation is generally repressive at high CpG density (…
A practical guide to the measurement and analysis of DNA methylation
BD Singer - American journal of respiratory cell and molecular …, 2019 - atsjournals.org
… Integration with ChIP-seq can be performed by examining DNA methylation at well-observed
CpGs across putative enhancers identified by occupancy of histone 3 lysine 4 …
CpGs across putative enhancers identified by occupancy of histone 3 lysine 4 …
DNA methylation methods: Global DNA methylation and methylomic analyses
S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… DNA methylation analysis technologies primarily based on the initial treatments of DNA …
For example, heavily methylated CpG sites were found in the gene bodies of transcriptional …
For example, heavily methylated CpG sites were found in the gene bodies of transcriptional …
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome
… Following the great acceptance of the human DNA methylation microarrays, … DNA methylation
microarray (Infinium Mouse Methylation BeadChip) that interrogates 280,754 unique CpG …
microarray (Infinium Mouse Methylation BeadChip) that interrogates 280,754 unique CpG …
Quantitative comparison of within-sample heterogeneity scores for DNA methylation data
… Most studies are limited to the average DNA methylation levels of individual CpGs and
thus neglect heterogeneity within the profiled cell populations. To assess this within-sample …
thus neglect heterogeneity within the profiled cell populations. To assess this within-sample …
[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics
… Subsequent studies combing MNase-seq and NOMe-seq data demonstrated that increasing
methylated CpG density was correlated with nucleosome occupancy in the human genome […
methylated CpG density was correlated with nucleosome occupancy in the human genome […
CoMeBack: DNA methylation array data analysis for co-methylated regions
… Then, since array-probe coverage of genomic CpGs is sparse, our algorithm would evaluate
… genomic CpGs of a specified density between them. We set the density of genomic CpGs …
… genomic CpGs of a specified density between them. We set the density of genomic CpGs …
Expression regulation of genes is linked to their CpG density distributions around transcription start sites
H Tian, Y He, Y Xue, YQ Gao - Life Science Alliance, 2022 - life-science-alliance.org
… We analyzed the RNA-seq, histone modification, and DNA methylation data of the liver,
lung… , and H3K36me3) and possess low DNA methylation levels around TSS, consistent with …
lung… , and H3K36me3) and possess low DNA methylation levels around TSS, consistent with …
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