Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans
K Ueno, Y Miyazaki - Allergology International, 2023 - jstage.jst.go.jp
… In bronchial pathology, IL-33M increased the level of mucus secreted by mucus producing
goblet cells, as visualized by periodic acid-Schiff (PAS) staining, whereas IL-33FL did not …
goblet cells, as visualized by periodic acid-Schiff (PAS) staining, whereas IL-33FL did not …
Adaptive immunology of Cryptococcus neoformans infections—an update
J Chen, J Shao, M Dai, W Fang, Y Yang - Frontiers in immunology, 2023 - frontiersin.org
… Furthermore, the fungal load and mucus production in mice increases significantly with
increased pulmonary allergic inflammation. Although Th1 cells play a protective role, Th2 cells …
increased pulmonary allergic inflammation. Although Th1 cells play a protective role, Th2 cells …
Dectin‐2‐mediated signaling triggered by the cell wall polysaccharides of Cryptococcus neoformans
D Tanno, R Yokoyama, K Kawamura… - Microbiology and …, 2019 - Wiley Online Library
… cells upon in vitro stimulation with C. neoformans. Furthermore, in in vivo experiments,
accelerated Th2 response and IL-4-dependent mucin production was observed in lungs infected …
accelerated Th2 response and IL-4-dependent mucin production was observed in lungs infected …
Functional Characterization of the GlcNAc Catabolic Pathway in Cryptococcus deneoformans
…, L Shen, Y Kuang, Y Wang, Y Peng, C Hu… - Applied and …, 2022 - Am Soc Microbiol
… size, melanin production, and antifungal drug resistance in Cryptococcus neoformans (9). …
GlcNAc in host lung mucins, the function of GlcNAc on host colonization of C. deneoformans …
GlcNAc in host lung mucins, the function of GlcNAc on host colonization of C. deneoformans …
Extension of O-Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans …
EJ Thak, YJ Son, DJ Lee, H Kim, JH Kim, SB Lee… - MBio, 2022 - Am Soc Microbiol
… has a null mutation of MSB2 encoding a mucin-like transmembrane protein involved in …
immune cells, we quantified the production of the proinflammatory cytokines tumor necrosis …
immune cells, we quantified the production of the proinflammatory cytokines tumor necrosis …
Intranasal inoculation of Cryptococcus neoformans in mice produces nasal infection with rapid brain dissemination
… intranasal infections and observed that all produce rapid brain dissemination. Additionally, …
Yeasts were abundant in airways, surrounded with a material that likely represented mucus …
Yeasts were abundant in airways, surrounded with a material that likely represented mucus …
Investigation of Antifungal Mechanisms of Thymol in the Human Fungal Pathogen, Cryptococcus neoformans
KW Jung, MS Chung, HW Bai, BY Chung, S Lee - Molecules, 2021 - mdpi.com
… neoformans is distinct from the conserved antifungal effect caused by ROS production in
other fungi. Our results show that thymol did not induce intracellular ROS production. In …
other fungi. Our results show that thymol did not induce intracellular ROS production. In …
A comparative study of IL-33 and its receptor ST2 in a C57BL/6 J mouse model of pulmonary Cryptococcus neoformans infection
Z Wang, Q Ma, J Jiang, X Yang, E Zhang, Y Tao… - Medical Microbiology …, 2023 - Springer
… In the present study, the reduced mucus production in the IL-33 −/− infected … mucus production
and survival extension. Of note, goblet cell hyperplasia and increased mucus production …
and survival extension. Of note, goblet cell hyperplasia and increased mucus production …
Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents
HH Lee, DJ Carmichael, V Ríbeiro, DN Parisi… - PLoS …, 2023 - journals.plos.org
… the cryptococcal cells stained with mucin carmine (indicated with arrows; Scale bar: 20 μm).
… [34,50], the ELISA and IF data produced in this investigation demonstrated that in delivery of …
… [34,50], the ELISA and IF data produced in this investigation demonstrated that in delivery of …
PAMPs and host immune response in cryptococcal infection
K Sato, K Kawakami - Medical Mycology Journal, 2022 - jstage.jst.go.jp
… anticryptococcal activity through production of nitric oxide. Clin … gamma-producing
Cryptococcus neoformans strain results in … mucin production in the lungs after pulmonary infection …
Cryptococcus neoformans strain results in … mucin production in the lungs after pulmonary infection …
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