Interleukin-17A: the key cytokine in neurodegenerative diseases

J Chen, X Liu, Y Zhong - Frontiers in aging neuroscience, 2020 - frontiersin.org
… Under IL-17A stimulation, miR-873 participates in inflammatory cytokine production in
astrocytes through the A20/NF-KB pathway in EAE mice (Liu X. et al., 2014; Shan et al., 2017; Liu X…

Exploring the etiological links behind neurodegenerative diseases: Inflammatory cytokines and bioactive kynurenines

M Tanaka, J Toldi, L Vécsei - International Journal of Molecular Sciences, 2020 - mdpi.com
… ALS is a degenerative disease leading to the dysfunction of … production [95]. In addition,
IDO-activated cells can alter the cytokine production of APCs to anti-inflammatory cytokines, TGF-…

Cytokines in inflammatory disease

S Kany, JT Vollrath, B Relja - International journal of molecular sciences, 2019 - mdpi.com
… age-related diseases especially of the eyes (eg, glaucoma or age-related macula degeneration)
has been … in vitro whole blood cells Increased IL-6 production by whole blood cells from …

The role of inflammation in retinal neurodegeneration and degenerative diseases

G Kaur, NK Singh - International Journal of Molecular Sciences, 2021 - mdpi.com
… The P2X7R upregulation has been shown to enhance inflammasome activation, which
leads to the release of proinflammatory cytokines and retinal degenerative diseases [86]. …

Inflammasomes in neuroinflammatory and neurodegenerative diseases

S Voet, S Srinivasan, M Lamkanfi… - EMBO molecular …, 2019 - embopress.org
… by secreting the inflammatory cytokines interleukin (IL)‐1β … of inflammasomes in common
degenerative diseases of the … , assessing their importance for cytokine production, pyroptosis, …

The regulatory role of IL-10 in neurodegenerative diseases

C Porro, A Cianciulli, MA Panaro - Biomolecules, 2020 - mdpi.com
… -mediated neuronal degeneration under pathological conditions. In … inhibiting the production
of pro-inflammatory cytokines, as … neurodegeneration and cytokines produced by activated …

The link between inflammaging and degenerative joint diseases

E Rezuș, A Cardoneanu, A Burlui, A Luca… - International journal of …, 2019 - mdpi.com
… forming a combination entitled cytokine network that can … OA disease activity being correlated
with the suppression of proinflammatory cytokine production such as IL-1β, TNF-α, and IL-6

[HTML][HTML] Degenerative osteoarthritis a reversible chronic disease

V Di Nicola - Regenerative therapy, 2020 - Elsevier
… OA is a progressive degenerative disease involving the entire joint structure in a vicious …
modulating immune cell proliferation and cytokine production. Interestingly, some immune cells …

The role of the inflammasome in neurodegenerative diseases

F Piancone, F La Rosa, I Marventano, M Saresella… - Molecules, 2021 - mdpi.com
… includes an increased production of pro-inflammatory cytokines, a reduced activity of Treg
… Interestingly, IL1β and IL-6 production was increased, whereas that of IL-10 was reduced in …

New insight into neurological degeneration: Inflammatory cytokines and blood–brain barrier

J Yang, M Ran, H Li, Y Lin, K Ma, Y Yang… - Frontiers in molecular …, 2022 - frontiersin.org
cytokines from systematic inflammation can also induce as much worse as from neurological
diseases or … of BBB, the main cytokines including IL-1β, TNFα, IL-6, and their mechanism on …