A perspective on targeting inflammation and cytokine actions in atherosclerosis
YH Chan, DP Ramji - Future medicinal chemistry, 2020 - Future Science
Atherosclerosis, a chronic inflammatory disorder of the … that inhibition of a specific proinflammatory
cytokine (IL-1β) yielded … on targeting inflammation for atherosclerosis, focusing on …
cytokine (IL-1β) yielded … on targeting inflammation for atherosclerosis, focusing on …
[HTML][HTML] Anti-inflammatory therapy for atherosclerosis: focusing on cytokines
AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
… When targeting inflammatory cytokines, some anti-atherosclerotic drugs are able to slow the
… atherosclerosis caused by lipid-lowering and reduces circulating inflammatory cytokines in …
… atherosclerosis caused by lipid-lowering and reduces circulating inflammatory cytokines in …
[HTML][HTML] New insight in HDACs: Potential therapeutic targets for the treatment of atherosclerosis
Y Luan, H Liu, Y Luan, Y Yang, J Yang… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis (AS) features include progressive hardening and reduced elasticity of
arteries. AS is the leading cause of morbidity and mortality. An increasing amount of evidence …
arteries. AS is the leading cause of morbidity and mortality. An increasing amount of evidence …
Key roles of inflammation in atherosclerosis: Mediators involved in orchestrating the inflammatory response and its resolution in the disease along with therapeutic …
YH Chan, DP Ramji - Atherosclerosis: Methods and Protocols, 2022 - Springer
… Cytokines have previously been recognized as promising therapeutic targets for atherosclerosis,
and a … cytokines attenuates disease progression [3, 4], supporting the critical role of …
and a … cytokines attenuates disease progression [3, 4], supporting the critical role of …
Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics
M Jin, J Fang, J Wang, X Shao, S Xu, P Liu… - Acta Pharmacologica …, 2023 - nature.com
… In recent years, TLRs have gained special attention as promising therapeutic targets for AS.
As the quest for increasingly effective medications is crucial, we discuss the involvement of …
As the quest for increasingly effective medications is crucial, we discuss the involvement of …
[HTML][HTML] Targeting early atherosclerosis: a focus on oxidative stress and inflammation
P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
… that MSTFs represent promising therapeutic targets for the prevention of atherosclerosis. Due
… and IL-18, both proinflammatory cytokines involved in the atherosclerotic process, are also …
… and IL-18, both proinflammatory cytokines involved in the atherosclerotic process, are also …
[HTML][HTML] The role of pro-inflammatory cytokines in the Pathogenesis of Cardiovascular Disease
H Zhang, NS Dhalla - International Journal of Molecular Sciences, 2024 - mdpi.com
… cytokines has been added to the repertoire of atherosclerotic pathophysiology over the last
decade. For example, IL-8 is generally considered a chemotactic cytokine … atherosclerosis, …
decade. For example, IL-8 is generally considered a chemotactic cytokine … atherosclerosis, …
Targeting VCAM-1: a therapeutic opportunity for vascular damage
MF Troncoso, MC Díaz-Vesga… - Expert Opinion on …, 2023 - Taylor & Francis
… , and interferon γ (IFN-γ) displayed additive effects on VCAM-1 expression at low concentrations,
VCAM-1 protein levels are lower at higher concentrations of the combined cytokines […
VCAM-1 protein levels are lower at higher concentrations of the combined cytokines […
Anticytokine agents: targeting interleukin signaling pathways for the treatment of atherothrombosis
PM Ridker - Circulation research, 2019 - Am Heart Assoc
… This review provides an overview of cytokines in atherosclerosis, the potential benefits
and risks associated with targeted anticytokine therapies, and a look to the future of clinical …
and risks associated with targeted anticytokine therapies, and a look to the future of clinical …
[HTML][HTML] Nucleic acid–based therapies for atherosclerosis
P Mäkinen, AK Ruotsalainen… - Current Atherosclerosis …, 2020 - Springer
… focuses on recent and novel nucleic acid–based therapies, which have advanced into clinical
development during the past 3 years and describe also new promising therapeutic targets …
development during the past 3 years and describe also new promising therapeutic targets …
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