[HTML][HTML] The pathogenesis of sepsis and potential therapeutic targets
M Huang, S Cai, J Su - International journal of molecular sciences, 2019 - mdpi.com
… response required for the clearance of bacterial infection [44]. Although a large portion of
sepsis patients might die during the initial cytokine storm, patients who survive this stage could …
sepsis patients might die during the initial cytokine storm, patients who survive this stage could …
Emerging therapeutic targets for sepsis
EW Tindal, BE Armstead, SF Monaghan… - Expert opinion on …, 2021 - Taylor & Francis
… In summary, while the innate immune system is rich in potential therapeutic targets and
remains a promising area of research, as has been demonstrated by the study of cytokines in this …
remains a promising area of research, as has been demonstrated by the study of cytokines in this …
[HTML][HTML] The role and mechanism of pyroptosis and potential therapeutic targets in sepsis: a review
X Zheng, W Chen, F Gong, Y Chen, E Chen - Frontiers in immunology, 2021 - frontiersin.org
… overview of the mechanisms and potential therapeutic targets underlying pyroptosis in sepsis
identified in recent decades, looking forward to the future direction of treatment for sepsis. …
identified in recent decades, looking forward to the future direction of treatment for sepsis. …
The pathogenesis and potential therapeutic targets in sepsis
W Zhang, H Jiang, G Wu, P Huang, H Wang, H An… - MedComm, 2023 - Wiley Online Library
… , which is seen as the primary driver of sepsis pathogenesis. Throughout the onset and
progression of sepsis, the generation of cytokines not only facilitates the activation of coagulation …
progression of sepsis, the generation of cytokines not only facilitates the activation of coagulation …
[HTML][HTML] Circulating histones in sepsis: potential outcome predictors and therapeutic targets
Y Li, D Wan, X Luo, T Song, Y Wang, Q Yu… - Frontiers in …, 2021 - frontiersin.org
… In summary, histone significantly contributed to the release of pro-inflammatory cytokines
and vascular endothelial injury in sepsis which unfortunately disrupt the fine balance and …
and vascular endothelial injury in sepsis which unfortunately disrupt the fine balance and …
[HTML][HTML] MDSCs in sepsis-induced immunosuppression and its potential therapeutic targets
W Zhang, X Fang, C Gao, C Song, Y He, T Zhou… - Cytokine & Growth …, 2023 - Elsevier
MDSCs in sepsis-induced immunosuppression and its potential therapeutic targets - … The
release of anti-inflammatory cytokines such as IL-10 and TGF-β contributes to sepsis-induced …
release of anti-inflammatory cytokines such as IL-10 and TGF-β contributes to sepsis-induced …
[HTML][HTML] Long non-coding RNAs as biomarkers and therapeutic targets in sepsis
C Wang, G Liang, J Shen, H Kong, D Wu… - Frontiers in …, 2021 - frontiersin.org
… sepsis, while enhancing M2 polarization might produce anti-inflammatory cytokines and
protect the body from sepsis … markers and potential therapeutic targets for patients with septic-…
protect the body from sepsis … markers and potential therapeutic targets for patients with septic-…
[HTML][HTML] A hub gene signature as a therapeutic target and biomarker for sepsis and geriatric sepsis-induced ARDS concomitant with COVID-19 infection
G Qian, H Fang, A Chen, Z Sun, M Huang… - Frontiers in …, 2023 - frontiersin.org
… potential therapeutic targets/biomarkers, sheds light on the immune response in geriatric
patients with sepsis… effect on COVID-19 and sepsis by affecting cytokine transport and release. …
patients with sepsis… effect on COVID-19 and sepsis by affecting cytokine transport and release. …
The role of HMGB1 in COVID‐19‐induced cytokine storm and its potential therapeutic targets: A review
S Wulandari, Hartono, T Wibawa - Immunology, 2023 - Wiley Online Library
… against SARS-CoV-2 infection leading to a cytokine storm was also evaluated. Moreover, …
cytokines produced might suppress many immune cells leading to uncontrolled viral infection …
cytokines produced might suppress many immune cells leading to uncontrolled viral infection …
Kinases as potential therapeutic targets for anti-coronaviral therapy
T Pillaiyar, S Laufer - Journal of Medicinal Chemistry, 2021 - ACS Publications
… the viral infection cycle (entry, replication, assembly, and egress), and several of them are
involved in the virus-induced hyperinflammatory response that leads to cytokine storm, acute …
involved in the virus-induced hyperinflammatory response that leads to cytokine storm, acute …
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