[HTML][HTML] Immunotherapy in sepsis-brake or accelerate?

F Steinhagen, SV Schmidt, JC Schewe… - Pharmacology & …, 2020 - Elsevier
… of the genes encoding the cytokines and mediators that … sepsis involves both the adaptive
and innate immune systems and is characterized by the release of anti-inflammatory cytokines, …

Role of the adaptive immune response in sepsis

J Brady, S Horie, JG Laffey - Intensive care medicine experimental, 2020 - Springer
… in sepsis survivors [49]. The protective effect of Th17 cells is also diminished following the
onset of sepsis [50] as is their cytokine … negatively impact outcome in sepsis by increasing the …

Blood purification techniques for sepsis and septic AKI

T Girardot, A Schneider, T Rimmele - Seminars in nephrology, 2019 - Elsevier
… trial Endotoxin and Cytokines Removal during continuous hemofiltration with oXiris (ECRO),
comparing a standard membrane and the oXiris filter in peritonitis-induced septic shock with …

[HTML][HTML] An update on sepsis biomarkers

MH Kim, JH Choi - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
… role in the inflammatory and cytotoxic response to sepsis including the synergic activation of
Toll-like receptors and the increase of production of pro-inflammatory cytokines [16]. Several …

Inflammation and cell death of the innate and adaptive immune system during sepsis

C Nedeva - Biomolecules, 2021 - mdpi.com
… of sepsis, although, it has been shown that NK cell numbers do markedly reduce during
sepsis and those cells remaining have impaired cytokine … of NK cells during sepsis leads to a …

New strategies for treatment of infectious sepsis

PA Ward, F Fattahi - Journal of leukocyte biology, 2019 - academic.oup.com
In this mini review, we describe the molecular mechanisms in polymicrobial sepsis that lead
to a series of adverse events including activation of inflammatory and prothrombotic …

Myeloid cells in sepsis‐acquired immunodeficiency

F Venet, J Demaret, M Gossez… - Annals of the New York …, 2021 - Wiley Online Library
… release of proinflammatory cytokines, excessive inflammatory response in sepsis includes the
… Blocking or eliminating inflammatory cytokines confers protection to sepsis in acute animal …

Sepsis and coronavirus disease 2019: common features and anti-inflammatory therapeutic approaches

J Beltran-Garcia, R Osca-Verdegal… - Critical care …, 2020 - journals.lww.com
… consisting on the use of the anakinra in sepsis showed positive effects on the outcome among
cytokine storm and improving the 28-day survival rate of patients with severe sepsis ( 31 ). …

Extracorporeal cytokine adsorption in septic shock: A proof of concept randomized, controlled pilot study

F Hawchar, I Laszlo, N Öveges, D Trasy, Z Ondrik… - Journal of critical …, 2019 - Elsevier
Background The aim of this proof of concept, prospective, randomized pilot trial was to
investigate the effects of extracorporeal cytokine removal (CytoSorb®) applied as a standalone …

Metabolic alterations in sepsis

W Wasyluk, A Zwolak - Journal of clinical medicine, 2021 - mdpi.com
… At this point, we would only like to emphasize the role of the cytokine storm in the pathogenesis
of sepsis. The most important pro-inflammatory cytokines are interleukin 1 (IL-1), IL-6 and …