Withdrawal of inhaled corticosteroids in COPD: a European Respiratory Society guideline

JD Chalmers, IF Laska, FME Franssen… - European …, 2020 - Eur Respiratory Soc
reductions: SGRQ score change of 4 points and FEV 1 change of 100 mL. The thresholds
for clinically important relative risk reductions … important absolute risk reductions were based …

Withdrawal of inhaled corticosteroids in COPD patients: rationale and algorithms

S Avdeev, Z Aisanov, V Arkhipov… - … Journal of Chronic …, 2019 - Taylor & Francis
… Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive
pulmonary disease: the COPE study. Am J Respir Crit Care Med. 2002;166:1358–1363. …

Withdrawal of inhaled corticosteroids versus continuation of triple therapy in patients with COPD in real life: observational comparative effectiveness study

H Magnussen, S Lucas, T Lapperre, JK Quint… - Respiratory …, 2021 - Springer
… This was an observational comparative effectiveness study aimed to evaluate the effect of
inhaled corticosteroid (ICS) cessation versus continuation of triple therapy in COPD patients. …

Inhaled corticosteroid withdrawal may improve outcomes in elderly patients with COPD exacerbation: a nationwide database study

T Jo, H Yasunaga, Y Yamauchi, A Mitani… - ERJ Open …, 2020 - Eur Respiratory Soc
… of corticosteroid prescriptions within 1 year after discharge in the ICS withdrawal group. …
infection, our findings suggest that ICS withdrawal may also reduce mild-to-moderate COPD …

The effect of inhaled corticosteroid withdrawal and baseline inhaled treatment on exacerbations in the IMPACT study. A randomized, double-blind, multicenter clinical …

MLK Han, GJ Criner, MT Dransfield… - American journal of …, 2020 - atsjournals.org
… effect of prior therapy, in particular inhaled corticosteroid (ICS) withdrawal, on study results.
… due to an ICS withdrawal effect. We did see a dampening of the reduction in moderate and …

Perceptions of COPD patients of the proposed withdrawal of inhaled corticosteroids prescribed outside guidelines: a qualitative study

G Gilworth, T Harries, C Corrigan… - Chronic Respiratory …, 2019 - journals.sagepub.com
… fixed combination inhaled corticosteroids (ICS) and long-acting β-agonists by symptomatic
patients with chronic obstructive pulmonary disease (COPD) who experience, or are at risk of, …

De-implementing inhaled corticosteroids to improve care and safety in COPD treatment: primary care providers' perspectives

K Stryczek, C Lea, C Gillespie, G Sayre… - Journal of general …, 2020 - Springer
… for discontinuing inhaled corticosteroids. Providers reported reluctance to discontinue
inhaled corticosteroids; even in cases they would otherwise discontinue inhaled corticosteroids. …

Asthma progression and mortality: the role of inhaled corticosteroids

P O'Byrne, LM Fabbri, ID Pavord, A Papi… - European …, 2019 - Eur Respiratory Soc
… Since ICS, particularly in combination with a LABA, can reduce the risk of severe asthma …
maintenance therapy may result in substantial withdrawal during such a study due to …

Optimizing de-escalation of inhaled corticosteroids in COPD: a systematic review of real-world findings

P Rogliani, BL Ritondo, M Gabriele… - Expert Review of …, 2020 - Taylor & Francis
… the rationale for withdrawal from inhaled corticosteroids (ICSs… risk reduction that increased
from 20.0% by the first month to 50.0% by the fourth month, and then stabilized. Risk reduction

Inhaled corticosteroid withdrawal and change in lung function in primary care patients with chronic obstructive pulmonary disease in England

HR Whittaker, K Wing, I Douglas, SJ Kiddle… - Annals of the …, 2022 - atsjournals.org
… the association between ICS withdrawal and the rate of FEV 1 … model the association between
ICS withdrawal and the rate of … Effects of withdrawal of inhaled steroids in men with severe …