Solubility Enhancement of Glipizide and Development of its Fast-dissolving Oral Film

HA Pawar, MSMA Momin - Current Drug Therapy, 2021 - ingentaconnect.com
… dispersion of the glipizide showed improved solubility by almost 10 folds. Many of the formulated
films … Conclusion: The solubility of Glipizide was improved successfully by solubilization …

[HTML][HTML] Formulation and characterization of glipizide solid dosage form with enhanced solubility

BS Alotaibi, MA Khan, K Ullah, H Yasin, A Mannan… - Plos one, 2024 - journals.plos.org
… The primary aim of this study was to explore the potential for enhancing the solubility and
dissolution rate of glipizide solid dosage form. This was achieved by creating solid dispersions …

Solubility measurement and various solubility parameters of glipizide in different neat solvents

MA Kalam, A Alshamsan, M Alkholief, IA Alsarra… - ACS …, 2020 - ACS Publications
… , increasing the solubility is an essential criterion for its enhanced bioavailability. The
solubility, dissolution, and eventually the bioavailability of GLZ can be improved by different …

[PDF][PDF] Use of glutaric acid to improve the solubility and dissolution profile of glipizide through pharmaceutical cocrystallization

F Batool, M Ahmad, MU Minhas, Q Khalid… - Acta Poloniae …, 2019 - bibliotekanauki.pl
… with various compounds and helps in their solubility enhancement. However, in previous
litera… study was to enhance the solubility and dissolution profile of glipizide by cocrystallization …

Formulation, characterization, and pharmacokinetic evaluation of novel glipizide-phospholipid nano-complexes with improved solubility and bio-availability

S Rathor, DC Bhatt - Pharmaceutical Nanotechnology, 2022 - ingentaconnect.com
… of the dissolving media significantly impacts glipizide dissolution, … pH, glipizide is a fundamental
molecule with enhanced solubility. … , the compound improved solubility and dissolution. …

Formulation and Evaluation of Glipizide Fast Dissolving Tablets

S Swati, RLS Suma, SN Prasanna… - Journal of …, 2020 - search.proquest.com
… This study shows that the disintegration and dissolution rate of Glipizide FDT enhanced to a
greater … of Glipizide for solubility and dissolution rate enhancement. IJPDA. 2014 Feb; 2(2). …

[PDF][PDF] STUDY OF DISSOLUTION ENHANCEMENT OF POORLY WATER SOLUBLE GLIPIZIDE BY USING SOLID DISPERSION TECHNIQUE

MS Mondal, MH Emon, SM Abuzar, MA Islam, MT Islam… - ijlsr.com
… (i) enhancing solubility and dissolution rate of poorly water-soluble drugs and (ii) enhancing
… technologies to improve the dissolution characteristics of poorly water-soluble drugs and in …

[PDF][PDF] ENHANCEMENT OF SOLUBILITY AND DISSOLUTION RATE OF GLIPIZIDE BY LIQUISOLID TECHNIQUE

IS Raj, RN Babu, I Sirisha, Y Sushmitha, M Sirisha - jcdronline.org
… flowing powder with enhanced dissolution rate. In the present study, Liqui-solid compacts is
applied to enhance the dissolution of the Glipizide Twenty two formulations of Glipizide were …

[HTML][HTML] Effect of raw material variability of glipizide on the in vitro dissolution rate and in vivo bioavailability performance: The importance of particle size

C Zhao, C Jin, H Gao, L Wang, H Liu, Z He - Asian journal of …, 2019 - Elsevier
… Similar with other class II drugs, the solubility of glipizide in gastrointestinal tract limits the
dissolution, and thus oral absorption and bioavailability in vivo [5]. Previous studies …

[PDF][PDF] DESIGN AND IN-VITRO EVALUATION OF INCLUSION COMPLEX OF WATER INSOLUBLE DRUG GLIPIZIDE

RA Khan, MM Iqbal, MA ur Rehman, A Khan - 2023 - wjpr.s3.ap-south-1.amazonaws.com
… increase the dissolution and bioavailability of poorly water-soluble drugs… solubility and
dissolution rate of Glipizide by solid dispersions (SDs) and investigate them for in vitro dissolution