DNA methylation analysis

L Feng, J Lou - Nanotoxicity: Methods and Protocols, 2019 - Springer
… the role of DNA methylation in both development and disease states [6, 7]. Detection of DNA
methylation is based on the ability to distinguish cytosine from 5mC in the DNA sequence. …

The SMART App: an interactive web application for comprehensive DNA methylation analysis and visualization

Y Li, D Ge, C Lu - Epigenetics & chromatin, 2019 - Springer
… To facilitate DNA methylation analysis, we present the SMART (Shiny Methylation Analysis
… web application for comprehensively analyzing the DNA methylation data of TCGA project. …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… In this review, we discuss the different DNA methylation analysis technologies primarily …
There have been multiple approaches developed for DNA methylation analysis technologies, …

A practical guide to the measurement and analysis of DNA methylation

BD Singer - American journal of respiratory cell and molecular …, 2019 - atsjournals.org
… topics in DNA methylation measurement and data analysis, … of mechanisms linking DNA
methylation to cellular function. … for the future of unsupervised DNA methylation analysis (60). …

Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders

B Sadikovic, MA Levy, J Kerkhof, E Aref-Eshghi… - Genetics in …, 2021 - nature.com
… We describe the clinical implementation of genome-wide DNA methylation analysis in rare
disorders across the EpiSign diagnostic laboratory network and the assessment of results …

RnBeads 2.0: comprehensive analysis of DNA methylation data

F Müller, M Scherer, Y Assenov, P Lutsik, J Walter… - Genome biology, 2019 - Springer
… To assist with an informed selection, we thus surveyed a broad range of tools for DNA
methylation analysis and assembled a detailed feature table based on the tool documentations (…

MethylNet: an automated and modular deep learning approach for DNA methylation analysis

JJ Levy, AJ Titus, CL Petersen, Y Chen, LA Salas… - BMC …, 2020 - Springer
… For the cancer subtype analysis, we sought to identify concordance between the latent
profiles of methylation across cancer types. Because each tumor type has a different baseline …

Detection of colorectal cancer in urine using DNA methylation analysis

S Bach, I Paulis, NR Sluiter, M Tibbesma, I Martin… - Scientific reports, 2021 - nature.com
… high-MW DNA present in urinary sediment is suitable for tumor DNA … of urine DNA methylation
analysis for detection of CRC. … is detectable through means of DNA methylation analysis. …

Methods for analysis of specific DNA methylation status

MJ Pajares, C Palanca-Ballester, R Urtasun… - Methods, 2021 - Elsevier
… This review highlights several considerations for specific DNA methylation analysis.
Understanding the type of information provided by and based on the advantages and limitations of …

DNA methylation changes associated with Parkinson's disease progression: outcomes from the first longitudinal genome-wide methylation analysis in blood

A Henderson-Smith, KM Fisch, J Hua, G Liu… - Epigenetics, 2019 - Taylor & Francis
… changes associated with PD progression: longitudinal analysis The main goal of our study
was to investigate whether blood DNA methylation changes as PD pathology progresses. To …