Joint profiling of DNA methylation and chromatin architecture in single cells

G Li, Y Liu, Y Zhang, N Kubo, M Yu, R Fang, M Kellis… - Nature …, 2019 - nature.com
chromatin states (Supplementary Fig. 4). … chromatin conformation and DNA methylation
together in single cells. Cellular heterogeneity presents a significant challenge for chromatin

DNA methylation-linked chromatin accessibility affects genomic architecture in Arabidopsis

Z Zhong, S Feng, SH Duttke… - Proceedings of the …, 2021 - National Acad Sciences
DNA methylation and chromatin accessibility, we performed assay for transposase-accessible
chromatin … show that chromatin accessibility anticorrelates with DNA methylation, as has …

Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

LF Rizzardi, PF Hickey, V Rodriguez DiBlasi… - Nature …, 2019 - nature.com
… We examined DNA methylation by whole-genome bisulfite sequencing in … chromatin
accessibility in the latter two. We find pronounced differences in both CpG and non-CpG methylation

Impact of DNA methylation on 3D genome structure

D Buitrago, M Labrador, JP Arcon, R Lema… - Nature …, 2021 - nature.com
… changes in global chromatin structure with a noticeable increase in gene condensation.
Overall, our results demonstrate that DNA methylation affects chromatin structure and function …

Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers

M Ando, Y Saito, G Xu, NQ Bui… - Nature …, 2019 - nature.com
… of DNA methylationDNA methylation, chromatin marks, and transcriptional alterations to
define the relationship between transcriptional modulation and spatial changes in chromatin

The role of DNA methylation in gene regulation

PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
… However, the relationship between DNA methylation and gene expression is … DNA
methylation and the underlying chromatin structure. The relationship between DNA methylation and …

Enhancer DNA methylation: implications for gene regulation

A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
DNA methylation involves the addition of a methyl group to the fifth carbon of the pyrimidine
cytosine ring (5-methylcytosine, 5mC). 5mC is widespread in vertebrate genomes where it is …

methyl-ATAC-seq measures DNA methylation at accessible chromatin

R Spektor, ND Tippens, CA Mimoso… - Genome …, 2019 - genome.cshlp.org
… abundance of methylation in less accessible chromatin over … sites of open chromatin and
DNA methylation states reported … chromatin and the methylation state of the underlying DNA. …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… Perhaps the hierarchical and highly regulated heterochromatization of the X chromosome
provides a unique chromatin environment that facilitates DNA methylation of X-linked CGIs. …

DNA methylation and chromatin accessibility predict age in the domestic dog

K Jin, BM McCoy, EA Goldman, V Usova… - Aging …, 2024 - Wiley Online Library
… have been built using DNA methylation (DNAm) profiles, … information—DNAm, and chromatin
accessibility as measured by … We found that chromatin accessibility can accurately predict …