H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
… DNA methylation and histone H3 lysine 4 methylation (8–10). These results, as well as data
from numerous other studies (11, 12), have increasingly supported the view that in addition …
from numerous other studies (11, 12), have increasingly supported the view that in addition …
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
… A supporting argument is that the removal of a chromatin assembly factor, CAF1, speeds up
methylation maintenance (126). Interestingly, UHRF1 decorates H3 tails with bulky ubiquitin …
methylation maintenance (126). Interestingly, UHRF1 decorates H3 tails with bulky ubiquitin …
Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation
… DNA methylation is an evolutionarily conserved epigenetic mechanism that critically influences
chromatin structure and function (1). In mammals, DNA methylation predominantly occurs …
chromatin structure and function (1). In mammals, DNA methylation predominantly occurs …
[HTML][HTML] RNA-directed DNA methylation
RM Erdmann, CL Picard - PLoS genetics, 2020 - journals.plos.org
… DNA methylation to specific DNA sequences. The RdDM pathway is unique to plants , although
other mechanisms of RNA-directed chromatin … The DNA methylation added by RdDM is …
other mechanisms of RNA-directed chromatin … The DNA methylation added by RdDM is …
[HTML][HTML] Physical activity and DNA methylation in humans
WJ Światowy, H Drzewiecka, M Kliber… - International Journal of …, 2021 - mdpi.com
… the chromatin structure and therefore modulate its accessibility for transcription factors. One
of such epigenetic mark is DNA methylation … DNA methylation is catalyzed by a family of DNA …
of such epigenetic mark is DNA methylation … DNA methylation is catalyzed by a family of DNA …
[HTML][HTML] Effects of DNA Methylation on Cancer and Aging
S Sevinç, O Erbaş - Journal of Experimental and Basic Medical Sciences, 2020 - jebms.org
… Recent evidence has shown that DNA methylation is associated with cancer and aging. It is
… in DNA methylation. In this review, it was mentioned that abnormal DNA methylation, which …
… in DNA methylation. In this review, it was mentioned that abnormal DNA methylation, which …
[HTML][HTML] The enigma of DNA methylation in the mammalian oocyte
H Demond, G Kelsey - F1000Research, 2020 - ncbi.nlm.nih.gov
… methylome and how it is established, focussing on recent insights from knockout models
in the mouse that explore the interplay between methylation and chromatin states. We also …
in the mouse that explore the interplay between methylation and chromatin states. We also …
Correlation patterns between DNA methylation and gene expression in the cancer genome atlas
… Here we present a pan-cancer analysis to examine the association between DNA methylation
and gene expression on an individual CpG basis. It is known that methylation of a single …
and gene expression on an individual CpG basis. It is known that methylation of a single …
Protective effects of zinc on rat sperm chromatin integrity involvement: DNA methylation, DNA fragmentation, ubiquitination and protamination after bleomycin …
… improvement in chromatin integrity, testicular organization and spermatogenesis when
administered after BEP, this research concentrated on the effect of BEP on DNA methylation and …
administered after BEP, this research concentrated on the effect of BEP on DNA methylation and …
[HTML][HTML] Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability
… molecules, we directly measured the DNA methylation level in H3K4me3-modified chromatin
using ChIP-bisulfite-sequencing (ChIP-BS-seq) [74, 75]. We identified H3K4me3 peaks …
using ChIP-bisulfite-sequencing (ChIP-BS-seq) [74, 75]. We identified H3K4me3 peaks …