A comparison of gene expression and DNA methylation patterns across tissues and species

LE Blake, J Roux, I Hernando-Herraez… - Genome …, 2020 - genome.cshlp.org
… , inter-tissue DNA methylation differences within a species … differences in DNA methylation
between any pair of tissues, a tissue-specific DMR is defined as having a similar methylation

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… our understanding of the roles of DNA methylation to various genomic contexts including
gene … describing DNA methylation patterns spawns a diversity of DNA methylation profiling …

[HTML][HTML] DNA methylation validation methods: a coherent review with practical comparison

Š Šestáková, C Šálek, H Remešová - Biological procedures online, 2019 - Springer
… There was no statistically significant difference in DNA methylation levels measured after …
We were able to accurately measured the DNA methylation in M and U regions. Obviously …

[HTML][HTML] Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

G Mansell, TJ Gorrie-Stone, Y Bao, M Kumari… - BMC genomics, 2019 - Springer
… aiming to identify DNA methylation differences associated with … threshold for identifying
DNA methylation sites that are … , we repeated our analyses on M-values to further interpret …

[HTML][HTML] What do DNA methylation studies tell us about depression? A systematic review

M Li, C D'Arcy, X Li, T Zhang, R Joober… - Translational psychiatry, 2019 - nature.com
… the role of sex in DNA methylation and post-traumatic stress disorder and major depressive
disorder (MDD), and suggested that sex differences in DNA methylation among those genes …

[HTML][HTML] DNA methylation: a historical perspective

AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
… rapidly growing number of base-resolution methylation maps. Despite this, several … of DNA
methylation patterns remain under investigation. Here, we review the field of DNA methylation

[HTML][HTML] Longitudinal DNA methylation differences precede type 1 diabetes

…, BI Frohnert, IV Yang, K Kechris, M Rewers… - Scientific Reports, 2020 - nature.com
… To summarize identified DNA methylation differences that preceded T1D, we tested for
enrichment of genes from DMP analyses using missMethyl 27 . No GO terms (Supplementary …

Latest techniques to study DNA methylation

Q Gouil, A Keniry - Essays in biochemistry, 2019 - portlandpress.com
DNA methylation is the process where methyl groups are added to DNA molecules which
changes the activity of the DNADNA methylation in cancer, the role of DNA methylation in the …

[HTML][HTML] Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals

PR Braun, S Han, B Hing, Y Nagahama… - Translational …, 2019 - nature.com
… In this study, we determined the extent to which peripheral tissues can be used as surrogates
for DNA methylation in the brain. Blood, saliva, buccal, and live brain tissue samples from …

[HTML][HTML] A DNA methylation atlas of normal human cell types

…, A Klochendler, I Fox-Fisher, S Shabi-Porat, M Hecht… - Nature, 2023 - nature.com
… is neither unmethylated nor methylated, thus reducing the block’s methylation difference and
… CpGs for U reads, and more than or equal to 75% methylated CpGs for M reads. We then …