Diverse and dynamic DNA modifications in brain and diseases

MJ Armstrong, Y Jin, EG Allen… - Human molecular …, 2019 - academic.oup.com
DNA methylation is a class of epigenetic modification essential for coordinating gene …
normal brain development and for proper brain function following development. Aberrant …

[HTML][HTML] The roles of human DNA methyltransferases and their isoforms in shaping the epigenome

H Gujar, DJ Weisenberger, G Liang - Genes, 2019 - mdpi.com
… This review mainly focuses on the role of DNMT3B and its isoforms in de novo methylation
and maintenance of DNA methylation, especially with respect to their role as an accessory …

[PDF][PDF] Profiling of DNA methylation patterns as biomarkers of human disease

V Modhukur - Tartu, Estonia: Tartu University.[Google Scholar], 2019 - core.ac.uk
… After predicting the DNA methylation biomarkers in selected … of DNA methylation patterns
as a biomarker to predict cancer patients’ survival in different cancer types. DNA methylation

Smoking and DNA methylation: correlation of methylation with smoking behavior and association with diseases and fetus development following prenatal exposure

D Fragou, E Pakkidi, M Aschner, V Samanidou… - Food and chemical …, 2019 - Elsevier
… risk for the development of a disease. This review summarizes the DNA methylation changes
… with smoking behavior and their association with various diseases and fetus development. …

[HTML][HTML] Altered DNA methylation pattern reveals epigenetic regulation of Hox genes in thoracic aortic dissection and serves as a biomarker in disease diagnosis

P Liu, J Zhang, D Du, D Zhang, Z Jin, W Qiu, X Zhou… - Clinical …, 2021 - Springer
DNA methylation in the development of TAD. This study explored alterations of the DNA
methylation … potential role of cell-free DNA (cfDNA) methylation as a biomarker in TAD diagnosis. …

[HTML][HTML] Epigenetic responses and the developmental origins of health and disease

D Goyal, SW Limesand, R Goyal - Journal of Endocrinology, 2019 - joe.bioscientifica.com
… These heritable modifications in gene expression occur through DNA methylation, histone
modification and noncoding RNA-associated gene activation or silencing, and all are defined …

Human age prediction using DNA methylation and regression methods

P Karir, N Goel, VK Garg - International Journal of Information Technology, 2020 - Springer
… whereas DNMT1 helps in maintaining the methylation during replication [13]. The proper
maintenance of DNA methylation is necessary for embryonic development, imprinting, and X-…

Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia

K Kobow, M Ziemann, H Kaipananickal, I Khurana… - …, 2019 - Wiley Online Library
… considered of uncertain significance as they were either absent or present with low frequency
(<1%) in public databases and have not been associated previously with human disease. …

[PDF][PDF] The DNA damage response-from cell biology to human disease

FC Lam - J. Transl. Genet. Genom, 2022 - researchgate.net
… Loss of function of these repair pathways leads to characteristic human disease phenotypes,
underlying the importance of DNA damage repair in the maintenance of human health and …

[PDF][PDF] Epigenetics and its essence in understanding human growth, development and disease

C Chukwuma Sr - J Med Res, 2022 - researchgate.net
… of DNA sequence and histones as well as DNA methylation. These epigenetic alterations
effect the growth of neurons in the developing … research in human diseaserelated epigenetic …