The role of epigenetics in the development of childhood asthma

C Qi, CJ Xu, GH Koppelman - Expert review of clinical immunology, 2019 - Taylor & Francis
… Study details of DNA methylation studies of … on human disease using epigenetics [Citation31].
The PACE asthma study combined a prospective design (newborn blood DNA methylation

[HTML][HTML] Discrimination of DNA methylation signal from background variation for clinical diagnostics

R Sanchez, X Yang, T Maher… - International journal of …, 2019 - mdpi.com
… Advances in the study of human DNA methylation variation offer a new avenue for the … DNA
methylation levels vary considerably in samples experiencing changes during development

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?

M Sallam, MA Benotmane, S Baatout, PJ Guns… - Epigenetics, 2022 - Taylor & Francis
… to cause DNA methylation alterations both in vitro and in vivo [Citation13–16]. Considering
the common occurrence of DNA methylation … of DNA methylation in radiation-induced CVD. …

[HTML][HTML] DNA hypermethylation and unstable repeat diseases: a paradigm of transcriptional silencing to decipher the basis of pathogenic mechanisms

L Poeta, D Drongitis, L Verrillo, MG Miano - Genes, 2020 - mdpi.com
… between DNA methylation and … development of promising molecular targeted-therapy
approaches. Indeed, here, we discuss general features of the paradigm of DNA hypermethylation–…

Mathematical models of DNA methylation dynamics: Implications for health and ageing

L Zagkos, M Mc Auley, J Roberts… - Journal of theoretical …, 2019 - Elsevier
DNA methylation, they fall short of fully capturing the dynamics of this process. In this paper
we develop … the key intracellular events which characterise DNA methylation. In particular the …

[HTML][HTML] Clopidogrel resistance is associated with DNA methylation of genes from whole blood of humans

J Yang, Q Yu, Z Xu, N Zheng, J Zhong, J Li, Y Liu… - Frontiers in …, 2021 - frontiersin.org
… However, it is rarely known about DNA methylation alterations in the peripheral blood of
subjects with CR. Alterations in DNA methylation modification could influence the expression …

[HTML][HTML] DNA methylation and brain structure and function across the life course: A systematic review

ENW Wheater, DQ Stoye, SR Cox, JM Wardlaw… - Neuroscience & …, 2020 - Elsevier
human disease, behaviour and cognition. This area of research is motivated by the understanding
that epigenetic processes contribute to brain developmentDNA methylation (DNAm) is …

DDT exposure during pregnancy and DNA methylation alterations in female offspring in the Child Health and Development Study

HC Wu, BA Cohn, PM Cirillo, RM Santella… - Reproductive …, 2020 - Elsevier
DNA methylation. Using prospective data from 316 daughters in the Child Health and
Development … prenatal exposure to DDTs and DNA methylation in blood collected in midlife (mean …

[HTML][HTML] Sex-specific DNA methylation differences in Alzheimer's disease pathology

L Zhang, JI Young, L Gomez, TC Silva… - Acta neuropathologica …, 2021 - Springer
… ROSMAP study with matched DNA methylation and RNA-seq … in DNA methylation data by
fitting the model methylation M … ; these are the ROSMAP methylation residuals. Similarly, we …

Parkinson's disease-associated shifts between DNA methylation and DNA hydroxymethylation in human brain in PD-related genes, including PARK19 (DNAJC6) and …

JI Choza, M Virani, NC Kuhn, M Adams, J Kochmanski… - 2024 - researchsquare.com
Background The majority of Parkinson’s disease (PD) cases are due to a complex interaction
between aging, genetics, and environmental factors; epigenetic mechanisms are thought …