The role of epigenetics in the development of childhood asthma
… Study details of DNA methylation studies of … on human disease using epigenetics [Citation31].
The PACE asthma study combined a prospective design (newborn blood DNA methylation …
The PACE asthma study combined a prospective design (newborn blood DNA methylation …
[HTML][HTML] Discrimination of DNA methylation signal from background variation for clinical diagnostics
… Advances in the study of human DNA methylation variation offer a new avenue for the … DNA
methylation levels vary considerably in samples experiencing changes during development …
methylation levels vary considerably in samples experiencing changes during development …
Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?
… to cause DNA methylation alterations both in vitro and in vivo [Citation13–16]. Considering
the common occurrence of DNA methylation … of DNA methylation in radiation-induced CVD. …
the common occurrence of DNA methylation … of DNA methylation in radiation-induced CVD. …
[HTML][HTML] DNA hypermethylation and unstable repeat diseases: a paradigm of transcriptional silencing to decipher the basis of pathogenic mechanisms
L Poeta, D Drongitis, L Verrillo, MG Miano - Genes, 2020 - mdpi.com
… between DNA methylation and … development of promising molecular targeted-therapy
approaches. Indeed, here, we discuss general features of the paradigm of DNA hypermethylation–…
approaches. Indeed, here, we discuss general features of the paradigm of DNA hypermethylation–…
Mathematical models of DNA methylation dynamics: Implications for health and ageing
L Zagkos, M Mc Auley, J Roberts… - Journal of theoretical …, 2019 - Elsevier
… DNA methylation, they fall short of fully capturing the dynamics of this process. In this paper
we develop … the key intracellular events which characterise DNA methylation. In particular the …
we develop … the key intracellular events which characterise DNA methylation. In particular the …
[HTML][HTML] Clopidogrel resistance is associated with DNA methylation of genes from whole blood of humans
J Yang, Q Yu, Z Xu, N Zheng, J Zhong, J Li, Y Liu… - Frontiers in …, 2021 - frontiersin.org
… However, it is rarely known about DNA methylation alterations in the peripheral blood of
subjects with CR. Alterations in DNA methylation modification could influence the expression …
subjects with CR. Alterations in DNA methylation modification could influence the expression …
[HTML][HTML] DNA methylation and brain structure and function across the life course: A systematic review
ENW Wheater, DQ Stoye, SR Cox, JM Wardlaw… - Neuroscience & …, 2020 - Elsevier
… human disease, behaviour and cognition. This area of research is motivated by the understanding
that epigenetic processes contribute to brain development… DNA methylation (DNAm) is …
that epigenetic processes contribute to brain development… DNA methylation (DNAm) is …
DDT exposure during pregnancy and DNA methylation alterations in female offspring in the Child Health and Development Study
HC Wu, BA Cohn, PM Cirillo, RM Santella… - Reproductive …, 2020 - Elsevier
… DNA methylation. Using prospective data from 316 daughters in the Child Health and
Development … prenatal exposure to DDTs and DNA methylation in blood collected in midlife (mean …
Development … prenatal exposure to DDTs and DNA methylation in blood collected in midlife (mean …
[HTML][HTML] Sex-specific DNA methylation differences in Alzheimer's disease pathology
… ROSMAP study with matched DNA methylation and RNA-seq … in DNA methylation data by
fitting the model methylation M … ; these are the ROSMAP methylation residuals. Similarly, we …
fitting the model methylation M … ; these are the ROSMAP methylation residuals. Similarly, we …
Parkinson's disease-associated shifts between DNA methylation and DNA hydroxymethylation in human brain in PD-related genes, including PARK19 (DNAJC6) and …
JI Choza, M Virani, NC Kuhn, M Adams, J Kochmanski… - 2024 - researchsquare.com
Background The majority of Parkinson’s disease (PD) cases are due to a complex interaction
between aging, genetics, and environmental factors; epigenetic mechanisms are thought …
between aging, genetics, and environmental factors; epigenetic mechanisms are thought …