DNA methylation profiling: an emerging paradigm for cancer diagnosis

A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
DNA methylation profiling is an additional emerging tool that … Tumor DNA methylation profiling
has led to the identification … In addition, DNA methylation patterns in circulating tumor DNA

Sarcoma classification by DNA methylation profiling

C Koelsche, D Schrimpf, D Stichel, M Sill… - Nature …, 2021 - nature.com
… We here describe a high stability of methylation profiles for sarcoma entities. In addition, our
… A practical example for the high stability of methylation profiles established by this approach …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… current and emerging DNA methylation and … DNA methylation profiling techniques. These
approaches hold promise for facilitating our comprehensive understanding of DNA methylation

DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management

F Nassiri, Y Mamatjan, S Suppiah… - Neuro …, 2019 - academic.oup.com
… have focused on molecular profiling of meningiomas to refine … shown that global DNA
methylation profiling reveals robust … To examine whether methylation profiles can be defined and …

Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancer

H Luo, Q Zhao, W Wei, L Zheng, S Yi, G Li… - Science translational …, 2020 - science.org
Circulating tumor DNA (ctDNA) has emerged as a useful diagnostic and prognostic biomarker
in many cancers. Here, we conducted a study to investigate the potential use of ctDNA …

The DNA methylation landscape in cancer

K Skvortsova, C Stirzaker, P Taberlay - Essays in biochemistry, 2019 - portlandpress.com
profiles and provides further insights into DNA methylation … distribution of DNA methylation
and DNA hydroxymethylation … Finally, we discuss DNA methylation profiling technologies …

Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
DNA methylation signature associated with severe COVID-19. (A) Overview of experimental
… comparative DNA methylation profiling. (B) Box and whisker plots of DNA methylation cell …

Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis

P Chai, J Yu, S Ge, R Jia, X Fan - Journal of hematology & oncology, 2020 - Springer
… not compare global DNA methylation level of KICH. Instead, we compared DNA methylation
level of KICH across different tumor stages, and we found that the DNA methylation was not …

Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases

P Jurmeister, M Bockmayr, P Seegerer… - Science Translational …, 2019 - science.org
… To address this, we performed DNA methylation profiling of primary tumors and trained three
different machine learning methods to distinguish metastatic HNSC from primary LUSC. We …

Targeted DNA methylation profiling of human cardiac tissue reveals novel epigenetic traits and gene deregulation across different heart failure patient subtypes

N Glezeva, B Moran, P Collier, CS Moravec… - Circulation: Heart …, 2019 - Am Heart Assoc
… Despite the vast clinical potential of DNA methylation sequencing not … methylation changes
in HF patients. In this study for the first time, we performed targeted DNA methylation profiling