Association of peripheral blood DNA methylation level with Alzheimer's disease progression
…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2021 - Springer
… model (robust regression), which is different from the nonlinear trajectory of cognitive decline
previously proposed in a hypothetical model … recall, Alzheimer Disease Assessment Scale-…
previously proposed in a hypothetical model … recall, Alzheimer Disease Assessment Scale-…
DNA methylation in the pathology of Alzheimer's disease: from gene to cognition
CH Poon, LSR Tse, LW Lim - Annals of the New York Academy …, 2020 - Wiley Online Library
… Although this study was conducted in a stress animal model, it still provides evidence from
an epigenetic perspective for NPAS4 as a possible target. Another molecule involved in tau …
an epigenetic perspective for NPAS4 as a possible target. Another molecule involved in tau …
DNA methylation variability in Alzheimer's disease
… we fitted a logistic regression model, in which methylation variability status (hypervariable or
… We found that the observed differential association of DNA methylation variability status with …
… We found that the observed differential association of DNA methylation variability status with …
Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease
…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2020 - Springer
… We analyzed differential DNA methylation across diagnosis groups using a mixed model
with a … Data collection and sharing for this project was funded by the Alzheimer's Disease …
with a … Data collection and sharing for this project was funded by the Alzheimer's Disease …
Prediction of Alzheimer's disease based on deep neural network by integrating gene expression and DNA methylation dataset
… We present a novel Alzheimer's disease prediction model based on deep neural network. …
based model that can predict AD using large-scale gene expression and DNA methylation data…
based model that can predict AD using large-scale gene expression and DNA methylation data…
DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health
… We assessed blood-based DNA methylation at 13 CpGs in the … Using linear mixed models
regression, we examined the … risks of Alzheimer's disease (AD) and cardiovascular disease. …
regression, we examined the … risks of Alzheimer's disease (AD) and cardiovascular disease. …
Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease
… To assess whether regions of the genome were differentially methylated between Alzheimer’s
disease cases and controls, we used bumphunter with the same models as above [26]. …
disease cases and controls, we used bumphunter with the same models as above [26]. …
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease
… utility of DNA methylation as clinical biomarkers, we also compared methylation differences
in … , we first removed confounding effects in DNA methylation data by fitting the model median …
in … , we first removed confounding effects in DNA methylation data by fitting the model median …
Sex-specific DNA methylation differences in Alzheimer's disease pathology
… in DNA methylation data by fitting the model methylation M … from this model; these are the
ROSMAP methylation residuals. … ] that are annotated to Alzheimer's disease, many of which are …
ROSMAP methylation residuals. … ] that are annotated to Alzheimer's disease, many of which are …
DNA methylation: a promising approach in management of Alzheimer's disease and other neurodegenerative disorders
G Kaur, SSS Rathod, MM Ghoneim, S Alshehri… - Biology, 2022 - mdpi.com
… , we summarize the association of DNA methylation with the … diseases, such as, Alzheimer’s
disease, Parkinson’s disease, … model, as well as in the 3xTg-AD mouse model, changes in …
disease, Parkinson’s disease, … model, as well as in the 3xTg-AD mouse model, changes in …
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