… drug passage into human milk’, ie. assessment or prediction of (variability of) drug
concentration-time profiles in human milk … nursing infants during maternal drug therapy. In this …

… transfer of medication into the human milk. However, reliable … in culture for at least 15 passages
and could represent a good … often applied to predict drug-drug interactions and to select …

… Determining the amount of drug transferred into human milk is critical for benefit–risk analysis
… pH of human milk during lactation, we conducted a sensitivity analysis by setting milk pH at …

… the passage of these drugs into human milk, often with conflicting results. Here, we sought
to evaluate the passage of selective serotonin reuptake inhibitors into human milk in the first …

… data on drug passage into breastmilk for individual drugs are often lacking and human studies
… , and usually studies have been done on drugs that have some human milk excretion data …

… due to the high molecular mass of the drug-protein complex, thus resulting in the … drug-protein
binding on drug transport across physiological barriers, whose role is to allow the passage …

… the passage of drugs into human milk. One historical approach still being used is the prediction
of the drug level in milk based on plasma concentration and using what is called the milk-…

… milk and summarized the effect of pregnancy on placental and of breastfeeding on mammal
gland drug … and M:P ratios of individual ARVs by drug class. Finally, we discussed the major …

… Because obtaining PK data is challenging during the early postpartum period and modeling
of drug passage into human breast milk has been limited, 22 we report the development of a …

… drug, to simulate infant drug exposure from human milk. … (240 and 433 mg) on drug exposure
during breastfeeding. … the 10th percentile due to increased milk intake. The simulated infant …