… of triple therapy. It is therefore necessary to clarify when the use of triple therapy is indicated
in COPD patients and when it is preferable to maintain treatment with dual bronchodilation. …

… evidence regarding fixed triple therapy as a therapeutic option and we summarize … therapy
from dual bronchodilation to triple therapy and step down from triple to double bronchodilation …

… Randomized trials report that single-inhaler triple therapy is more effective than dual
bronchodilators … single-inhaler triple therapy with dual bronchodilators in real-world clinical …

… = standard error; TRIBUTE = extrafine inhaled triple therapy versus dual bronchodilator
therapy in chronic obstructive pulmonary disease trial; TRINITY = single inhaler extrafine triple …

… These data show that therapeutic intervention is effective in treatment-naïve patients.
Intervention with dual bronchodilator therapy as a first maintenance treatment for COPD may …

… Randomized trials of triple therapy including an inhaled … dual bronchodilators, likely resulting
from ICS withdrawal at randomization. We compared triple therapy with dual bronchodilator …

… therapy, dual bronchodilator agents with a combination of LABA and LAMA was an important
therapy … D) should be treated with dual bronchodilator agents initially, according to the …

… -bronchodilator therapy in stable chronic obstructive pulmonary disease (COPD), the choice
of mono-therapy or dual-therapy … We investigate whether dual therapy is more effective than …

… Two reviewers (PR and LC) performed a comprehensive literature search from May 25th
2019 to May 30th 2019 for RCTs evaluating the impact of dual bronchodilation therapy in …

… therapy (TT; long-acting muscarinic antagonists (LAMAs)/long-acting inhaled β-agonists (LABAs)/inhaled
corticosteroids (ICSs)) versus dual bronchodilation … /LAMA therapy and had two …