Clinical significance of the bronchodilator response in children with severe asthma

AM Coverstone, LB Bacharier, BS Wilson… - Pediatric …, 2019 - Wiley Online Library
… 12% relative BD response had a longer duration of asthma, … that after 180 µg of albuterol,
the average response in SA met the … bronchodilation. Our study suggests that while a 12% BD …

Bronchodilator responsiveness as a predictor of success for bronchial thermoplasty

D Langton, A Ing, D Fielding, W Wang, V Plummer… - …, 2019 - Wiley Online Library
duration and severity, remodelling of the airway is known to occur in some patients, with
subsequent loss of acute responsiveness to bronchodilator.3, … of bronchodilator reversibility is a …

An evaluation of single and dual long-acting bronchodilator therapy as effective interventions in maintenance therapy-naïve patients with COPD

D Singh, AD D'Urzo, JF Donohue… - … Journal of Chronic …, 2019 - Taylor & Francis
therapy-naïve patients, these findings suggest that earlier intervention with a dual bronchodilator
maintenance therapybronchodilator therapy as a first maintenance treatment for COPD. …

Determinants of response to bronchodilator in patients with cough variant asthma-A randomized, single-blinded, placebo-controlled study

F Yi, L Han, B Liu, X Zhang, Y Xue, W Luo… - Pulmonary …, 2020 - Elsevier
response to bronchodilator in patients with CVA, and the factors associated with response to
bronchodilator … be doubted that such a short duration of treatment would affect the efficacy of …

Beyond dual bronchodilation–triple therapy, when and why

M Cazzola, P Rogliani, R Laitano… - … Journal of Chronic …, 2022 - Taylor & Francis
… a key factor in the duration of action of LABAs whereas partitioning of the drug into lipophilic
compartments after inhalation is the key determinant of their long duration of action. LABAs …

Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - ASPET
… of bronchodilator and in identifying novel classes of bronchodilator drugs. However, new
classes of … This review discusses recent advancements in knowledge on bronchodilators and …

Rationale and clinical use of bronchodilators in adults with bronchiectasis

MÁ Martínez-García, G Oscullo, A García-Ortega… - Drugs, 2022 - Springer
… 3–12 months of bronchodilator therapy (the duration of bronchodilator use was different in
bronchodilator response can predict responsiveness to long-term bronchodilator therapy in …

Immediate bronchodilator response in FEV1 as a diagnostic criterion for adult asthma

LE Tuomisto, P Ilmarinen, L Lehtimäki… - European …, 2019 - Eur Respiratory Soc
Asthma is characterised by variable and reversible expiratory airflow limitations. Thus, it is
logical to use the change in forced expiratory volume in 1 s (FEV 1 ) in response to a …

Deterioration of nighttime respiratory mechanics in COPD: impact of bronchodilator therapy

NJ Domnik, MD James, RE Scheeren, GA Ayoo… - Chest, 2021 - Elsevier
… , optimization of nighttime bronchodilation is an important goal of management. Our results
set the stage for future studies to determine whether extending their duration of action during …

Responsiveness to parenteral corticosteroids and lung function trajectory in adults with moderate-to-severe asthma

LC Denlinger, BR Phillips, RL Sorkness… - American journal of …, 2021 - atsjournals.org
… lose lung function despite therapy. We hypothesized that participants with the smallest responses
to … (22, 29, 39), and in this study, the subgroup that improved post-bronchodilator FEV 1 …