Efficacy and safety of first line treatments for patients with advanced epidermal growth factor receptor mutated, non-small cell lung cancer: systematic review and …

YI Zhao, J Liu, X Cai, Z Pan, J Liu, W Yin, H Chen, Z Xie… - Bmj, 2019 - bmj.com
Lung cancer is the leading cause of cancer related deaths worldwide, and non-small cell
lung cancer (NSCLC) accounts for about 85% of overall reported cases.A clinically significant …

[HTML][HTML] … efficacy and safety data and impact of the EML4-ALK fusion variant on the efficacy of alectinib in untreated ALK-positive advanced non–small cell lung cancer …

DR Camidge, R Dziadziuszko, S Peters, T Mok… - Journal of Thoracic …, 2019 - Elsevier
efficacy with ALK inhibitors, including alectinib.3, 8 Here we report updated efficacy and safety
… 1, 2017) and an exploratory analysis of efficacy by EML4-ALK fusion variant. We discuss …

[HTML][HTML] Efficacy and safety of combined brain radiotherapy and immunotherapy in non-small-cell lung cancer with brain metastases: a systematic review and meta …

Y Yang, L Deng, Y Yang, T Zhang, Y Wu, L Wang… - Clinical Lung Cancer, 2022 - Elsevier
Lung cancer remains the leading cause of cancer-related morbidity and mortality worldwide
1 . Non-small-cell lung cancer (… as having advanced or metastatic lung cancer at the time of …

[HTML][HTML] Efficacy and safety of first-line carboplatin-versus cisplatin-based chemotherapy for non-small cell lung cancer: A meta-analysis

F Griesinger, EE Korol, S Kayaniyil, N Varol, T Ebner… - Lung Cancer, 2019 - Elsevier
… of first-line (1L) therapy for advanced non-small cell cancer (NSCLC). The objective of this
study was to evaluate the relative efficacy, safety, and health-related quality of life (HRQoL) of …

Efficacy and safety of rovalpituzumab tesirine in third-line and beyond patients with DLL3-expressing, relapsed/refractory small-cell lung cancer: results from the phase …

D Morgensztern, B Besse, L Greillier… - Clinical Cancer …, 2019 - AACR
… Small-cell lung cancer (SCLC) accounts for approximately 13% to 15% of all lung cancers
with an estimate of more than 180,000 new cases diagnosed annually worldwide (1–3). This …

[HTML][HTML] Comparative efficacy and safety for different chemotherapy regimens used concurrently with thoracic radiation for locally advanced non-small cell lung cancer …

T Liu, Z He, J Dang, G Li - Radiation Oncology, 2019 - Springer
Lung cancer remains the leading cause of cancer-associated deaths globally. Non-small
cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases [1] and …

[HTML][HTML] Real-world efficacy and safety of anlotinib with and without immunotherapy in advanced non-small cell lung cancer

Q Xiong, B Qin, L Xin, B Yang, Q Song, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer-…
About 80%–85% of patients have non-small cell lung cancers (NSCLC), and most have locally …

LBA2 ALINA: efficacy and safety of adjuvant alectinib versus chemotherapy in patients with early-stage ALK+ non-small cell lung cancer (NSCLC)

BJ Solomon, JS Ahn, R Dziadziuszko… - Annals of …, 2023 - annalsofoncology.org
Background For patients (pts) with resected, stage IB–IIIA, ALK+ NSCLC, the recommended
treatment after surgery is platinum-based chemotherapy (CT), which is associated with …

[HTML][HTML] Clinical efficacy and safety of maintenance therapy for advanced non-small cell lung cancer: a retrospective real-world study

X Xu, R Li, P Zhu, P Zhang, J Chen, Y Lin… - World Journal of Surgical …, 2021 - Springer
Lung cancer remains the leading global cause of cancer-… cell lung cancer (NSCLC) accounts
for 85% of all lung cancers … is safe and effective for treating advanced squamous cell lung

Efficacy and safety of pembrolizumab plus docetaxel vs docetaxel alone in patients with previously treated advanced non–small cell lung cancer: The PROLUNG …

O Arrieta, F Barrón, LA Ramírez-Tirado… - JAMA …, 2020 - jamanetwork.com
Importance Because of socioeconomic factors, many patients with advanced non–small cell
lung cancer (NSCLC) do not receive immunotherapy in the first-line setting. It is unknown if …