[HTML][HTML] The role of DNA methylation in epigenetics of aging

A Unnikrishnan, WM Freeman, J Jackson… - Pharmacology & …, 2019 - Elsevier
… is embryonically lethal because DNA methylation patterns are … DNA methylation has evolved
from one in which methylation … braoder perspective where DNA methylation is dynamically …

Epigenetic control of a local chromatin landscape

AM Chiarella, D Lu, NA Hathaway - International journal of molecular …, 2020 - mdpi.com
… For the purposes of this review, we focus primarily on the contribution of DNA methylation
stability of DNA methylation to progress through cell replication [27,28]. The DNA methylation “…

Epigenetic control of transcriptional regulation in pluripotency and early differentiation

D Gökbuget, R Blelloch - Development, 2019 - journals.biologists.com
… results in a gain of DNA methylation over these non-CGI … ESCs for opposing widespread
DNA methylation. Overall, … and DNA methylation, which is essential for the epigenetic landscape …

Enhancer DNA methylation: implications for gene regulation

A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
DNA methylation involves the addition of a methyl group to the fifth carbon of the pyrimidine
cytosine ring (5-methylcytosine, 5mC). 5mC is widespread in vertebrate genomes where it is …

DNA methylation and regulation of gene expression: Guardian of our health

GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
DNA methylation and demethylation. Resultantly, differentiated cells inherit a unique DNA
methylation … Although apparently a stable epigenetic mark, DNA methylation is actually labile …

DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
Epigenetic reprogramming in the germline involves the erasure of somatic lineage epigenetic
marks (including DNA methylation) in PGCs and subsequent establishment of germ cell-…

DNA methylation at the crossroads of gene and environment interactions

PP Law, ML Holland - Essays in biochemistry, 2019 - portlandpress.com
… Although this epigenetic behaviour is genetically … exposures may influence epigenetic control
of gene expression and … , DNA methylation is the most frequently assayed epigenetic mark …

DNA methylation as a transcriptional regulator of the immune system

L Morales-Nebreda, FS McLafferty, BD Singer - Translational Research, 2019 - Elsevier
DNA methylation is a dynamic epigenetic modification with a … the ability to measure DNA
methylation on a genome-wide … for studying how DNA methylation patterning modulates cell …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… of DNA methylation in embryonic, germline and somatic cell development. Finally, we provide
insights into DNA methylation … germlines; these epigenetically imprinted patterns withstand …

Dynamics of DNA methylation and its functions in plant growth and development

S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
… Role of DNA methylation in stress tolerance and epigenetic stress memory in plants.
Abiotic stresses may alter the expression of the stress-responsive genes and cause …