… This review focuses on the known families of DNA methylation … Epigenetic therapies (“Epi-therapies”)
targeting the components of the epigenome are emerging as potential therapeutic …

… of DNA methylation in embryonic, germline and somatic cell development. Finally, we provide
insights into DNA methylation … germlines; these epigenetically imprinted patterns withstand …

… hematological malignancies and has exhibited viable therapeutic potential for solid tumors
in … of enzymes in DNA methylation, histone acetylation and histone methylation during tumor …

… of epigenetic dysregulation in AML, discuss the available epigenetic therapies, and forecast
… As such, DNA methylation provides an epigenetic method for controlling gene expression. …

… This hallmark is also an emerging target for immunotherapy in combination with epigenetic
therapy. Drugs blocking DNMT activity have led to remarkable improvement in patient …

… and drugs that affect methylation for the clinical … epigenetic molecular biomarkers for the
early clinical diagnosis of different types of liver cancer, and whether epigenetic therapeutic …

… Alteration of normal DNA methylation has been well profiled for over 25 years of epigenetic
studies … , but also the enzyme for pre-mRNA splicing could be epigenetic therapeutic targets. …

… Epigenetic therapies seek to normalize DNA methylation patterns and post-translational …
could alter DNA methylation has raised hopes for extending the epigenetic therapeutic portfolio. …

… By interrogating the methylation status in liquid biopsies, … DNA methylation changes also
drive EMT and therapy resistance in a clinical setting. Particularly, by monitoring methylation …

… We show that the DNA methylation landscape of patient CART19 cells influences the
efficacy of the cellular immunotherapy treatment in patients with B-cell malignancy. …